Which anthropometric measurements including visceral fat, subcutaneous fat, body mass index, and waist circumference could predict the urinary stone composition most?

BMC Urology

Research Article

Soon-Sun Kwon¹  Seong Sook Hong²  Jiyoung Hwang²  Kang Su Cho³  Won Jae Yang⁴  Seung Whan Doo⁴  Yun Seob Song⁴  Jae Heon Kim⁴ 

[1] Biomedical Research Institute, Seoul National University Bundang Hospital, Seongnam, Korea;Department of Radiology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine Seoul, Seoul, Korea;Department of Urology, Gangnam Severance Hospital, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea;Department of Urology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea;

关键词: Urinary calculi;    Obesity;    Body mass index;    Visceral fat;    Computed tomography;   

DOI  :  10.1186/s12894-015-0013-x

 received in 2014-11-02, accepted in 2015-02-26,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundAlthough there is growing evidence of relationship between obesity and some specific stone compositions, results were inconsistent. Due to a greater relationship between metabolic syndrome and some specific stone type, obesity measured by body mass index (BMI) has limitation in determining relationship between obesity and stone compositions. The aim of this study was to determine the relationship among BMI, visceral fat, and stone compositions.MethodsWe retrospectively reviewed data of patients with urinary stone removed over a 5 year period (2011–2014). Data on patient age, gender, BMI, urinary pH, stone composition, fat volumes (including visceral fat, subcutaneous fat, total fat, waist circumference), and ratio for visceral to total fat using computed tomography based delineation were collected. To figure out the predicting factor while adjusting other confounding factors, discriminant analysis was used.ResultsAmong 262 cases, average age was 52.21 years. Average BMI and visceral fat were 25.03 cm2 and 124.75 cm2, respectively. By chi square test, there was significant (p < 0.001) difference in stone types according to sex. By ANOVA test, BMI, visceral fat, visceral to subcutaneous fat ratio, the percentage of visceral fat and total fat showed significant association with stone types. By discriminant analysis, visceral fat was proved to be a powerful factor to predict stone composition (structure matrix of visceral fat = −0.735) with 42.0% of predictive value.ConclusionVisceral fat adiposity strongly related with uric acid stone and has better predictive value than BMI or urinary pH to classify the types of stone.

【 授权许可】

Unknown   
© Kim et al.; licensee BioMed Central. 2015. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.