Mastectomy for management of breast cancer in Ibadan, Nigeria

BMC Surgery

Research Article

Temidayo O Ogundiran¹  Adeyinka F Ademola¹  Omobolaji O Ayandipo²  Clement A Adebamowo³ 

[1] Division of Oncology, Department of Surgery, College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria;Division of Oncology, Department of Surgery, University College Hospital, PMB 5116, Ibadan, Nigeria;Division of Oncology, Department of Surgery, University College Hospital, PMB 5116, Ibadan, Nigeria;Institute of Human Virology, Abuja, Nigeria;Department of Epidemiology and Preventive Medicine, University of Maryland, Maryland, USA;

关键词: Breast cancer;    Mastectomy;    Nigeria;   

DOI  :  10.1186/1471-2482-13-59

 received in 2013-05-13, accepted in 2013-12-10,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundModified radical mastectomy remains the standard therapeutic surgical operation for breast cancer in most parts of the world. This retrospective study reviews mastectomy for management of breast cancer in a surgical oncology division over a ten year period.MethodsWe reviewed the case records of consecutive breast cancer patients who underwent mastectomy at the Surgical Oncology Division, University College Hospital (UCH) Ibadan between November 1999 and October 2009.ResultsOf the 1226 newly diagnosed breast cancer patients over the study period, 431 (35.2%) patients underwent mastectomy making an average of 43 mastectomies per year. Most patients were young women, premenopausal, had invasive ductal carcinoma and underwent modified radical mastectomy as the definitive surgical treatment. Prior to mastectomy, locally advanced tumors were down staged in about half of the patients that received neo-adjuvant combination chemotherapy. Surgical complication rate was low. The most frequent operative complication was seroma collection in six percent of patients. The average hospital stay was ten days and most patients were followed up at the surgical outpatients department for about two years post-surgery.ConclusionsThere was low rate of mastectomy in this cohort which could partly be attributable to late presentation of many patients with inoperable local or metastatic tumors necessitating only palliative or terminal care. Tumor down-staging with neo-adjuvant chemotherapy enhanced surgical loco-regional tumor control in some patients. The overall morbidity and the rates of postoperative events were minimal. Long-term post-operative out-patients follow-up was not achieved as many patients were lost to follow up after two years of mastectomy.

【 授权许可】

CC BY   
© Ogundiran et al.; licensee BioMed Central Ltd. 2013