Long-term impact of intrauterine fetal death on quality of life and depression: a case–control study

BMC Pregnancy and Childbirth

Research Article

Øivind Ekeberg¹  Ida Kathrine Gravensteen²  Linda Bjørk Helgadottir³  Per Morten Sandset⁴  Eva-Marie Jacobsen⁴ 

[1] Department of Acute Medicine, Oslo University Hospital, Ulleval, Oslo, Norway;Department of Behavioural Sciences in Medicine, University of Oslo, Oslo, Norway;Department of Haematology, Oslo University Hospital, Ulleval, Box 4950, N-0424, Nydalen, Oslo, Norway;Department of Behavioural Sciences in Medicine, University of Oslo, Oslo, Norway;Department of Haematology, Oslo University Hospital, Ulleval, Box 4950, N-0424, Nydalen, Oslo, Norway;Department of Obstetrics and Gynaecology, Oslo University Hospital, Ulleval, Oslo, Norway;Institute of Clinical Medicine, University of Oslo, Oslo, Norway;Department of Haematology, Oslo University Hospital, Ulleval, Box 4950, N-0424, Nydalen, Oslo, Norway;Institute of Clinical Medicine, University of Oslo, Oslo, Norway;

关键词: Intrauterine fetal death;    Quality of life;    Depression;    Well-being;    Socioeconomic status;   

DOI  :  10.1186/1471-2393-12-43

 received in 2011-12-23, accepted in 2012-06-07,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundIntrauterine fetal death (IUFD) is a serious incidence that has been shown to impact mothers’ psychological well-being in the short-term. Long-term quality of life (QOL) and depression after IUFD is not known. This study aimed to determine the association between intrauterine fetal death and long-term QOL, well-being, and depression.MethodsAnalyses were performed on collected data among 106 women with a history of intrauterine fetal death (IUFD) and 262 women with live births, 5–18 years after the event. Univariable and multivariable linear and logistic regression models were used to quantify the association between previous fetal death and long-term QOL, well-being and depression. QOL was assessed using the QOL Index (QLI), symptoms of depression using the Center for Epidemiological Studies Depression Scale (CES-D), and subjective well-being using the General Health Questionnaire 20 (GHQ-20).ResultsMore of the cases had characteristics associated with lower socioeconomic status and did not rate their health as good as did the controls. The QLI health and functioning subscale score was slightly but significantly lower in the cases than in the controls (22.3. vs 23.5, P = .023). The CES-D depressed affect subscale score (2.0 vs 1.0, P = 0.004) and the CES-D global score (7.4 vs 5.0, P = .017) were higher in the cases. Subjective well-being did not differ between groups (20.6 vs 19.4, P = .094). After adjusting for demographic and health-related variables, IUFD was not associated with global QOL (P = .674), subjective well-being (P = .700), or global depression score (adjusted odds ratio = 0.77, 95% confidence interval 0.37–1.57).ConclusionsWomen with previous IUFD, of which the majority have received short-term interventions, share the same level of long-term QOL, well-being and global depression as women with live births only, when adjusted for possible confounders.Trial registrationThe study was registered at http://www.clinicaltrials.gov, with registration number NCT 00856076.

【 授权许可】

Unknown   
© Gravensteen et al.; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.