High prevalence of type 2 diabetes among the urban middle class in Bangladesh

BMC Public Health

Research Article

Masuma Akter Khanam¹  Tahmeed Ahmed²  Shuchi Anand³  Glenn M Chertow³  Mark R Cullen⁴  Michele Barry⁵  Juliann Saquib⁶  Nazmus Saquib⁶ 

[1] Centre for Control of Chronic Diseases, International Center on Diarrheal Diseases and Research (ICDDR, B), Dhaka, Bangladesh;Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Newcastle upon Tyne, Australia;Centre for Nutrition and Food Security, International Center on Diarrheal Diseases and Research (ICDDR, B), Dhaka, Bangladesh;Stanford University School of Medicine, Division of Nephrology, Stanford University, Stanford, USA;Stanford University School of Medicine, General Medical Disciplines, Stanford University, Stanford, CA, USA;Stanford University School of Medicine, Global Health, Stanford University, Stanford, USA;Stanford University School of Medicine, Stanford Prevention Research Center (SPRC), Stanford University, Stanford, USA;

关键词: Insulin Resistance;    Metabolic Syndrome;    Middle Class;    Smokeless Tobacco;    Wealth Index;   

DOI  :  10.1186/1471-2458-13-1032

 received in 2013-04-03, accepted in 2013-10-23,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundThe prevalence of type-2 diabetes and metabolic syndrome are increasing in the developing world; we assessed their prevalence among the urban middle class in Bangladesh.MethodsIn this cross-sectional survey (n = 402), we randomly selected consenting adults (≥ 30 years) from a middle-income neighborhood in Dhaka. We assessed demography, lifestyle, and health status, measured physical indices and blood pressure and obtained blood samples. We evaluated two primary outcomes: (1) type-2 diabetes (fasting blood glucose ≥ 7.0 mmol/L or hemoglobin A1C ≥ 6.5% (48 mmol/mol) or diabetes medication use) and (2) insulin resistance (type-2 diabetes or metabolic syndrome using International Diabetes Federation criteria).ResultsMean age and Quételet’s (body mass) index were 49.4 ± 12.6 years and 27.0 ± 5.1 kg/m2; 83% were married, 41% had ≥12 years of education, 47% were employed, 47% had a family history of diabetes. Thirty-five percent had type-2 diabetes and 45% had metabolic syndrome. In multivariate models older age and family history of diabetes were significantly associated with type-2 diabetes. Older age, female sex, overweight or obese, high wealth index and positive family history of diabetes were significantly associated with insulin resistance. Participants with type-2 diabetes or insulin resistance had significantly poorer physical health only if they had associated cardiovascular disease.ConclusionsThe prevalence of type-2 diabetes and metabolic syndrome among the middle class in Dhaka is alarmingly high. Screening services should be implemented while researchers focus on strategies to lessen the incidence and morbidity associated with these conditions.

【 授权许可】

Unknown   
© Saquib et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.