Validation of metabolic syndrome using medical records in the SUN cohort

BMC Public Health

Research Article

Maria Teresa Barrio-Lopez¹  Martin Garcia-Lopez¹  Juan Jose Beunza²  Maira Bes-Rastrollo²  Alejandro Fernandez-Montero²  Miguel Angel Martinez-Gonzalez² 

[1] Department of Cardiology and Cardiovascular Surgery, Clínica Universidad de Navarra, Avenida de Pio XII, 36, 31008, Pamplona, Navarra, Spain;Department of Preventive Medicine and Public Health. School of Medicine, University of Navarra, C/Irunlarrea, 1, 31008, Pamplona, Navarra, Spain;

关键词: Metabolic Syndrome;    Waist Circumference;    International Diabetes Federation;    Kappa Index;    Metabolic Syndrome Component;   

DOI  :  10.1186/1471-2458-11-867

 received in 2011-07-31, accepted in 2011-11-15,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundThe objective of this study was to evaluate the validity of self reported criteria of Metabolic Syndrome (MS) in the SUN (Seguimiento Universidad de Navarra) cohort using their medical records as the gold standard.MethodsWe selected 336 participants and we obtained MS related data according to Adult Treatment Panel III (ATP III) and International Diabetes Federation (IDF). Then we compared information on the self reported diagnosis of MS and MS diagnosed in their medical records. We calculated the proportion of confirmed MS, the proportion of confirmed non-MS and the intraclass correlation coefficients for each component of the MS.ResultsFrom those 336 selected participants, we obtained sufficient data in 172 participants to confirm or reject MS using ATP III criteria. The proportion of confirmed MS was 91.2% (95% CI: 80.7- 97.1) and the proportion of confirmed non-MS was 92.2% (95% CI: 85.7-96.4) using ATP III criteria. The proportion of confirmed MS using IDF criteria was 100% (95% CI: 87.2-100) and the proportion of confirmed non-MS was 97.1% (95% CI: 85.1-99.9). Kappa Index was 0.82 in the group diagnosed by ATP III criteria and 0.97 in the group diagnosed by IDF criteria. Intraclass correlation coefficients for the different component of MS were: 0.93 (IC 95%:0.91- 0.95) for BMI; 0.96 (IC 95%: 0.93-0.98) for waist circumference; 0.75 (IC 95%: 0.66-0.82) for fasting glucose; 0.50 (IC 95%:0.35-0.639) for HDL cholesterol; 0.78 (IC 95%: 0.70-0.84) for triglycerides; 0.49 (IC 95%:0.34-0.61) for systolic blood pressure and 0.55 (IC 95%: 0.41-0.65) for diastolic blood pressure.ConclusionsSelf-reported MS based on self reported components of the SM in a Spanish cohort of university graduates was sufficiently valid as to be used in epidemiological studies.

【 授权许可】

Unknown   
© Barrio-Lopez et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.