Peripheral capillary non-perfusion in asymptomatic Waldenström's macroglobulinemia

BMC Ophthalmology

Case Report

Dimitris Papaconstantinou¹  Chryssanthi Koutsandrea¹  Ilias Georgalas¹  Ioannis Ladas¹  Athanasios Kotsolis¹ 

[1] Department of Ophthalmology, " G.Gennimatas" Hospital, University of Athens, Athens, Greece;

关键词: Retinal Detachment;    Retinal Hemorrhage;    Vascular Plexus;    Macroglobulinemia;    Indirect Ophthalmoscopy;   

DOI  :  10.1186/1471-2415-10-30

 received in 2010-05-18, accepted in 2010-12-03,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundTo report the rare association of peripheral retinal ischemia in a patient with Waldenström's macroglobulinemia.Case PresentationA 39-year old man with a recent diagnosis of asymptomatic Waldenström's macroglobulinemia (WM) was referred from his physician for ocular evaluation. The fundus examination in his right eye (RE) revealed very mild central vein dilation, while retinal hemorrhages associated with microaneurismal alterations of the vascular plexus were detected at the temporal periphery. Fluoroscein angiography of his RE revealed an extended area of capillary dropout distal to the microaneurismal lesions. In our patient with WM an extensive area of capillary non-perfusion, in the absence of severe involvement of the posterior pole was documented; this association to the best of our knowledge has never been reported before.ConclusionAlthough the incidence of the disease is rare, meticulous examination of the retinal periphery should be performed in all patients with WM and vice versa the differential diagnosis of peripheral retinal ischemia of unknown origin should include an investigation to rule out asymptomatic Waldenström's macroglobulinemia.

【 授权许可】

Unknown   
© Koutsandrea et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.