Human meningitis due to Streptococcus suis in Lomé, Togo: a case report

BMC Infectious Diseases

Case Report

Corinne Marois-Créhan¹  Mireille Prince-David²  Mounerou Salou²  Céline Plainvert³  Asmaa Tazi⁴  Claire Poyart⁴  Komi Assogba⁵  Koffi A. Balogou⁵ 

[1] Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail, 22440, Ploufragan, France;Université Bretagne Loire, 22440, Ploufragan, France;Centre de Biologie Moléculaire et d’Immunologie, Université de Lomé, BP 101, Lomé, Togo;Service de Microbiologie, Centre Hospitalier Universitaire Sylvanus Olympio, Tokoin Hôpital, BP 57, Lomé, Togo;Service de Bactériologie, Hôpitaux Universitaires Paris Centre, site Cochin, 75679, Paris cedex 14, France;Centre National de Référence des Streptocoques, Hôpital Cochin, 75679, Paris cedex 14, France;Service de Bactériologie, Hôpitaux Universitaires Paris Centre, site Cochin, 75679, Paris cedex 14, France;Centre National de Référence des Streptocoques, Hôpital Cochin, 75679, Paris cedex 14, France;Université Paris Descartes, 75006, Paris, France;Service de Neurologie, Centre Hospitalier Universitaire Campus, BP 30284, Lomé, Togo;

关键词: Case report;    Streptococcus suis;    Meningitis;    Zoonosis;    Neurologic sequelae;    Capsular serotype;   

DOI  :  10.1186/s12879-016-2006-0

 received in 2016-08-24, accepted in 2016-10-29,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundStreptococcus suis is a zoonotic pathogen which represents the leading cause of meningitis in Southeast Asia and an emerging pathogen in the Western world, the main risk factor for infection being contact with pigs. In Africa, the prevalence of S. suis infections in swine and humans is largely unrecognized, with only one recent report of a limited case series.Case presentationWe describe a human case of meningitis due to S. suis in a 32-year-old man living in Togo. The patient had no particular medical history and no risk factors for immunodeficiency but reported regular contact with pork products. Using specific immunological and molecular methods, we characterized the isolate as S. suis serotype 2, ST1, one the most prevalent and virulent clone worldwide. The outcome was favorable after one week of adapted antibiotic therapy but the patient was left with severe hearing disorders.ConclusionsThis work highlights the emergence of this pathogen in Africa and reinforces the need for accurate epidemiological and surveillance studies of S. suis infections and for educating clinicians and exposed groups in non-endemic countries.

【 授权许可】

CC BY   
© The Author(s). 2016