期刊论文详细信息
BMC Pulmonary Medicine
Health effects of the Federal Bureau of Prisons tobacco ban
Study Protocol
Joseph R DiFranza1  Melissa Foster1  Stephen A Martin2  Stephen J Krinzman3  Robert J Goldberg4  Herbert Beam5  Sandra Howard5  Bartolome R Celli6  Jennifer G Clarke7 
[1] Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, 01655, Worcester, MA, USA;Department of Family Medicine and Community Health, University of Massachusetts Medical School, Barre Family Health Center, 151 Worcester Road, 01005, Barre, MA, USA;Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, 01655, Worcester, MA, USA;Department of Quantitative Health Sciences, University of Massachusetts Medical School, 55 Lake Avenue North, 01655, Worcester, MA, USA;Federal Bureau of Prisons, Federal Medical Center, Devens, P.O. Box 880, 01432, Ayer, MA, USA;Harvard Medical School, Brigham and Women’s Hospital, Pulmonary and Critical Care Medicine, 75 Francis Street, 02115, Boston, MA, USA;The Warren Alpert Medical School of Brown University, 111 Brewster Street, CPCP 2nd floor, 02860, Pawtucket, RI, USA;
关键词: Pulmonary disease;    Chronic Obstructive Pulmonary Disease;    Asthma;    Pathophysiology;    Biomarkers;    Pulmonary function tests;    Tobacco;    Nicotine;    Addiction;    Health services;   
DOI  :  10.1186/1471-2466-12-64
 received in 2012-04-12, accepted in 2012-10-08,  发布年份 2012
来源: Springer
PDF
【 摘 要 】

BackgroundTobacco smoking remains the leading cause of preventable death in America, claiming 450,000 lives annually. Chronic Obstructive Pulmonary Disease, caused by smoking in the vast majority of cases, became the third leading cause of death in the U.S. in 2008. The burden of asthma, often exacerbated by tobacco exposure, has widespread clinical and public health impact. Despite this considerable harm, we know relatively little about the natural history of lung disease and respiratory impairment in adults, especially after smoking cessation.Methods/DesignOur paper describes the design and rationale for using the 2004 Federal Bureau of Prisons tobacco ban to obtain insights into the natural history of respiratory diseases in adult men and women of different races/ethnicities who are imprisoned in federal medical facilities. We have developed a longitudinal study of new prison arrivals, with data to be collected from each participant over the course of several years, through the use of standardized questionnaires, medical chart reviews, lung function tests, six-minute walk tests, and stored serum for the analysis of present and future biomarkers. Our endpoints include illness exacerbations, medication and health services utilization, lung function, serum biomarkers, and participants’ experience with their health and nicotine addiction.DiscussionWe believe the proposed longitudinal study will make a substantial contribution to the understanding and treatment of respiratory disease and tobacco addiction.

【 授权许可】

CC BY   
© Martin et al.; licensee BioMed Central Ltd. 2012

【 预 览 】
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