Aerobic training for improved memory in patients with stress-related exhaustion: a randomized controlled trial

BMC Psychiatry

Research Article

Carl-Johan Boraxbekk¹  Therese Eskilsson²  Hanna Malmberg Gavelin³  Lisbeth Slunga Järvholm⁴  Anna Stigsdotter Neely⁵ 

[1] Danish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark;Center for Demographic and Aging Research (CEDAR), Umeå University, Umeå, Sweden;Umeå Centre for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden;Department of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, SE- 901 87, Umeå, Sweden;Department of Psychology, Umeå University, Umeå, Sweden;Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå University, Umeå, Sweden;Department of Social and Psychological Studies, Karlstad University, Karlstad, Sweden;

关键词: Cognition;    Episodic memory;    Exercise;    Burnout;    Anxiety;    Depression;   

DOI  :  10.1186/s12888-017-1457-1

 received in 2017-02-27, accepted in 2017-08-08,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundPatients with stress-related exhaustion suffer from cognitive impairments, which often remain after psychological treatment or work place interventions. It is important to find effective treatments that can address this problem. Therefore, the aim of this study was to investigate the effects on cognitive performance and psychological variables of a 12-week aerobic training program performed at a moderate-vigorous intensity for patients with exhaustion disorder who participated in a multimodal rehabilitation program.MethodsIn this open-label, parallel, randomized and controlled trial, 88 patients diagnosed with exhaustion disorder participated in a 24-week multimodal rehabilitation program. After 12 weeks in the program the patients were randomized to either a 12-week aerobic training intervention or to a control group with no additional training. Primary outcome measure was cognitive function, and secondary outcome measures were psychological health variables and aerobic capacity.ResultsIn total, 51% patients in the aerobic training group and 78% patients in the control group completed the intervention period. The aerobic training group significantly improved in maximal oxygen uptake and episodic memory performance. No additional improvement in burnout, depression or anxiety was observed in the aerobic group compared with controls.ConclusionAerobic training at a moderate-vigorous intensity within a multimodal rehabilitation program for patients with exhaustion disorder facilitated episodic memory. A future challenge would be the clinical implementation of aerobic training and methods to increase feasibility in this patient group.Trial registrationClinicalTrials.gov: NCT03073772. Retrospectively registered 21 February 2017.

【 授权许可】

CC BY   
© The Author(s). 2017