期刊论文详细信息
BMC Cancer
Analysing population-based cancer survival – settling the controversies
Research Article
Bernard Rachet1  Maja Pohar Perme2  Jacques Estève3 
[1] Cancer Survival Group, Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, WC1E 7HT, London, UK;Institute of Biostatistics and Medical Informatics, Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000, Ljubljana, Slovenia;Université Claude Bernard, Hospices Civils de Lyon, Service de Biostatistique, 162 Avenue Lacassagne, 69003, Lyon, France;
关键词: Relative survival;    net survival;    Cancer registries;    Population-based studies;   
DOI  :  10.1186/s12885-016-2967-9
 received in 2016-07-21, accepted in 2016-11-23,  发布年份 2016
来源: Springer
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【 摘 要 】

BackgroundThe relative survival field has seen a lot of development in the last decade, resulting in many different and even opposing suggestions on how to approach the analysis.MethodsWe carefully define and explain the differences between the various measures of survival (overall survival, crude mortality, net survival and relative survival ratio) and study their differences using colon and prostate cancer data extracted from the national population-based cancer registry of Slovenia as well as simulated data.ResultsThe colon and prostate cancer data demonstrate clearly that when analysing population-based data, it is useful to split the overall mortality in crude probabilities of dying from cancer and from other causes. Complemented by net survival, it provides a complete picture of cancer survival in a given population. But when comparisons of different populations as defined for example by place or time are of interest, our simulated data demonstrate that net survival is the only measure to be used.ConclusionsThe choice of the method should be done in two steps: first, one should determine the measure of interest and second, one should choose among the methods that estimate that measure consistently.

【 授权许可】

CC BY   
© The Author(s). 2016

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