Antibacterial activity of a sterile antimicrobial polyisoprene surgical glove against transient flora following a 2-hours simulated use

BMC Surgery

Research Article

Michael Schäffer¹  Peter Starzengruber²  Johannes Leitgeb³  Rupert Schuster³  Julian-Camill Harnoss⁴  Ojan Assadian⁵  Bit New Yee⁶  Pui Fong Chee⁶ 

[1] Department for General, Visceral, and Thoracic Surgery, Marienhospital Stuttgart, Böheimstrasse 37, D-70199, Stuttgart, Germany;Department for Hospital Hygiene, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria;Department for Trauma Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria;Department of General, Visceral and Transplant Surgery, University Hospital Heidelberg, Im Neuenheimer Feld 110, D-69120, Heidelberg, Germany;Institute for Skin Integrity and Infection Prevention, School of Human & Health Sciences, R1/29 Ramsden Building, University of Huddersfield, HD1 3DH, Huddersfield, UK;Science & Technology Innovation Centre, Ansell Shah Alam, 40000, Shah Alam, Selangor, Malaysia;

关键词: Antimicrobial;    Surgical glove;    Transient flora;    Antibacterial efficacy;    Suppression;   

DOI  :  10.1186/s12893-015-0058-5

 received in 2013-09-23, accepted in 2015-05-25,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundA surgical glove will protect surgeons and patients only if the glove’s integrity remains intact. However, several studies have demonstrated that undetected micro-perforations of surgical gloves are common. Because of the possibility of surgical glove puncture, an antimicrobial surgical glove was developed. The aim of this laboratory based experimental study was to assess the antibacterial efficacy of the interior chlorhexidine-gluconate (CHG)-coat of an antimicrobial synthetic polyisoprene surgical glove by using a standardized microbiological challenge.MethodsSixteen healthy adult participants donned one antimicrobial surgical glove and one non-antimicrobial surgical glove randomly allocated to their dominant and non-dominant hand following a crossover design. During a 2-h wear time, participants performed standardized finger and hand movements. Thereafter, the interior surface of excised fingers of the removed gloves was challenged with 8.00 log10 cfu/mL S. aureus (ATCC 6538) or K. pneumoniae (ATCC 4352), respectively. The main outcome measure was the viable mean log10 cfu counts of the two glove groups after 5 min contact with the interior glove’s surface.ResultsWhen comparing an antimicrobial glove against an untreated reference glove after 2-h simulated use wear-time, a mean reduction factor of 6.24 log10 (S. aureus) and 6.22 log10 (K. pneumoniae) was achieved after 5 min contact.ConclusionThese results demonstrate that wearing antibacterial gloves on hands does not negatively impact their antibacterial activity after 2-h of wear. This may have a potential benefit for patient safety in case of glove puncture during surgical procedures.

【 授权许可】

Unknown   
© Leitgeb et al. 2015. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.