Silver doped metal layers for medical applications

22nd International Laser Physics Workshop

Kocourek, T.^1,2 ; Jelínek, M.^1,2 ; Mikovský, J.^1,2 ; Jurek, K.^1 ; Weiserová, M.^3

Institute of Physics AS CR, Na Slovance 2, 182 21 Praha 8, Czech Republic^1

Czech Technical University in Prague, Faculty of Biomedical Engineering, nam. Sitna 3105, 27201 Kladno, Czech Republic^2

Institute of Microbiology ASCR, Videnska cesta 1083, Praha 4, Czech Republic^3

关键词: Antibacterial efficacy;    Bacillus Subtilis;    Doped materials;    KrF excimer laser;    Metallic silver;    Physical and mechanical properties;    Surface wettability;    Titanium alloy Ti6Al4V;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/497/1/012021/pdf
DOI  :  10.1088/1742-6596/497/1/012021

来源: IOP

【 摘 要 】

Biological, physical and mechanical properties of silver-doped layers of titanium alloy Ti6Al4V and 316L steel prepared by pulsed laser deposition were studied. Metallic silver-doped coatings could be a new route for antibacterial protection in medicine. Thin films of silver and silver-doped materials were synthesized using KrF excimer laser deposition. The materials were ablated from two targets, which were composed either from titanium alloy with silver segments or from steel with silver segments. The concentration of silver ranged from 1.54 at% to 4.32 at% for steel and from 3.04 at% to 13.05 at% for titanium alloy. The layer properties such as silver content, structure, adhesion, surface wettability, and antibacterial efficacy (evaluated by Escherichia coli and Bacillus subtilis bacteria) were measured. Film adhesion was studied using scratch test. The antibacterial efficacy changed with silver doping up to 99.9 %. Our investigation was focused on minimum Ag concentration needed to reach high antibacterial efficiency, high film adhesion, and hardness.