Safety of liver resection and effect on quality of life in patients with benign hepatic disease: Single center experience

BMC Surgery

Research Article

Peter Neuhaus¹  Sabine Engel¹  Carsten Kamphues¹  Roberta Bova¹  Gero Puhl¹  Michael Hippler-Benscheidt¹  Daniel Seehofer¹  Timm Denecke² 

[1] Department of General, Visceral and Transplantation Surgery, Universitätsklinikum Charité, Campus Virchow Klinikum, Humboldt-Universität, D-13353, Berlin, Germany;Department of Radiology, Universitätsklinikum Charité, Campus Virchow Klinikum, Humboldt-Universität, D-13353, Berlin, Germany;

关键词: Liver Resection;    Hemangioma;    Hepatic Resection;    Focal Nodular Hyperplasia;    Liver Cyst;   

DOI  :  10.1186/1471-2482-11-16

 received in 2011-02-14, accepted in 2011-07-26,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundAlthough liver resection has long been established for selected patients with benign hepatic disease, the success of surgical treatment of these patients cannot be evaluated exclusively through postoperative morbidity and mortality. Therefore, the aim of the study was to prove the safety of liver resection in the treatment of benign liver tumors and to evaluate the effect of surgical treatment on the patients' qauality of life.MethodsA total of 146 patients who underwent liver resection because of benign liver tumors were included in this study. Postoperative outcome was assessed and patients evaluated their quality of life before surgery and at the present time using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 (QLQ C-30).ResultsThe rate of serious (> grade 2) complications was 4.1% with no postoperative death. The quality of life assessment revealed an overall improvement of general health status after resection (0.7 vs. 0.56, p < 0.001) and additionally a significant reduction of 6 out of 9 symptoms. Furthermore, compelling benefits in the patients' social and emotional coping could be detected after surgery.ConclusionsLiver resection for benign liver disease is a safe procedure and leads to a significant improvement of quality of life in selected patients.

【 授权许可】

CC BY   
© Kamphues et al; licensee BioMed Central Ltd. 2011