Trajectories of the relationships of physical activity with body composition changes in older men: the MrOS study

BMC Geriatrics

Research Article

Neeta Parimi¹  Peggy M. Cawthon²  Iva Miljkovic³  Eric Orwoll⁴  Deepika R. Laddu⁵  Andrew R. Hoffman⁶  Marcia L. Stefanick⁷ 

[1] California Pacific Medical Center Research Institute, San Francisco, California, USA;California Pacific Medical Center Research Institute, San Francisco, California, USA;Department of Epidemiology and Biostatics, University of California, San Francisco, CA, USA;Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA;Department of Medicine, Oregon Health & Sciences University, Portland, OR, USA;Department of Physical Therapy, University of Illinois at Chicago, 60612, Chicago, Illinois, USA;Division of Endocrinology, Gerontology and Metabolism, Department of Medicine, Stanford University, Palo Alto, California, USA;Stanford Prevention Research Center, Department of Medicine, Stanford University, Stanford, California, USA;

关键词: Physical activity;    Lean mass;    Fat mass;    Older men;    Trajectories;   

DOI  :  10.1186/s12877-017-0506-4

 received in 2016-12-28, accepted in 2017-05-22,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundExcess adiposity gains and significant lean mass loss may be risk factors for chronic disease in old age. Long-term patterns of change in physical activity (PA) and their influence on body composition decline during aging has not been characterized. We evaluated the interrelationships of PA and body composition at the outset and over longitudinal follow-up to changes in older men.MethodsSelf-reported PA by the Physical Activity Scale for the Elderly (PASE), clinic body weight, and whole-body lean mass (LM) and fat mass, by dual-energy x-ray absorptiometry (DXA), were assessed in 5964 community-dwelling men aged ≥65 years at baseline (2000–2002) and at two subsequent clinic visits up until March 2009 (an average 4.6 and 6.9 years later). Group-based trajectory modeling (GBTM) identified patterns of change in PA and body composition variables. Relationships of PA and body composition changes were then assessed.ResultsGBTM identified three discrete trajectory patterns, all with declining PA, associated primarily with initial PA levelshigh-activity (7.2% of men), moderate-activity (50.0%), and low-activity (42.8%). In separate models, GBTM identified eight discrete total weight change groups, five fat mass change groups, and six LM change groups. Joint trajectory modeling by PA and body composition group illustrated significant declines in total weight and LM, whereas fat mass levels were relatively unchanged among high-activity and low-activity-declining groups, and significantly increased in the moderate-activity-declining group.ConclusionAlthough patterns of change in PA and body composition were identified, groups were primarily differentiated by initial PA or body composition rather than by distinct trajectories of change in these variables.

【 授权许可】

CC BY   
© The Author(s). 2017