A pilot study to evaluate the feasibility of individualized yoga for inpatient children receiving intensive chemotherapy

BMC Complementary and Alternative Medicine

Research Article

Michelle Lee¹  Deborah Tomlinson¹  Tanya Hesser¹  Caroline Diorio¹  Cathy O’Sullivan¹  Lillian Sung²  Christine Armstrong³  Janine Piscione³  Tal Schechter³  George Tomlinson⁴ 

[1]Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, M5G 0A4, 686 Bay St, Toronto, ON, Canada

[2]Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, M5G 0A4, 686 Bay St, Toronto, ON, Canada

[3]Division of Haematology/Oncology, The Hospital for Sick Children, M5G 1X8, 555 University Ave, Toronto, ON, Canada

[4]Division of Haematology/Oncology, The Hospital for Sick Children, M5G 1X8, 555 University Ave, Toronto, ON, Canada

[5]Toronto General Hospital, M5G 2C4, 200 Elizabeth Street, Toronto, ON, Canada

关键词: Pilot;    Yoga;    Children;    Chemotherapy;    Haematopoietic stem cell transplantation;    Fatigue;    Quality of life;   

DOI  :  10.1186/s12906-015-0529-3

 received in 2014-02-05, accepted in 2015-01-16,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundFatigue is an important problem in paediatric cancer patients and yoga may be an effective intervention. The primary objective was to determine the feasibility of individualized yoga for hospitalized children receiving intensive chemotherapy.MethodsWe included English-speaking children and adolescents aged 7–18 years receiving intensive chemotherapy or haematopoietic stem cell transplantation (HSCT). Yoga was conducted three times weekly for three weeks. The primary outcome was feasibility, defined as ability to deliver at least 60% of planned sessions. Secondary outcomes were parent-reported Pediatric Quality of Life Inventory (PedsQL) Multidimensional Fatigue Scale, Fatigue Scale-Parent, PedsQL Generic Core Scales and PedsQL Acute Cancer Module.ResultsBetween January and October 2013, 11 patients were enrolled. Median age was 14.0 (range 7.7-16.4) years and 6 (55%) were boys. Yoga was feasible with 10/11 participants meeting the threshold for feasibility. The median number of yoga sessions was 9 (range 3–13). No adverse events were attributed to yoga. Mean ± standard deviation for the day 21 proxy-reported PedsQL general fatigue scores was 55.6 ± 15.5. Qualitative comments suggested design changes for future yoga studies.ConclusionsIndividualized yoga is feasible for inpatient children receiving intensive chemotherapy. Future work will include development and conduct of a randomized trial for fatigue amelioration.Trial registrationClinicalTrials.gov NCT02105389.

【 授权许可】

Unknown   
© Diorio et al.; licensee BioMed Central. 2015. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.