Neuroticism, depression and anxiety in takotsubo cardiomyopathy

BMC Cardiovascular Disorders

Research Article

Lia E. Bang¹  Lene Holmvang¹  Thomas Emil Christensen²  Søren Dinesen Østergaard³  Andreas Kjær⁴  Philip Hasbak⁴  Per Bech⁵ 

[1] Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark;Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark;Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Copenhagen University Hospital, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark;Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark;Department P - Research, Aarhus University Hospital, Risskov, Denmark;Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Copenhagen University Hospital, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark;Psychiatric Research Unit, Psychiatric Center North Zealand, Copenhagen University Hospital, Hillerød, Denmark;

关键词: Takotsubo cardiomyopathy;    Well-being;    Neuroticism;    Depression;    Anxiety;   

DOI  :  10.1186/s12872-016-0277-4

 received in 2015-11-27, accepted in 2016-05-13,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundTakotsubo cardiomypathy (TTC) causes acute reversible heart failure. Prior studies have indicated that the syndrome is associated with traits such as social inhibition, chronic psychological stress, and anxio-depressive disorders. The objective of this study was to further characterize key psychological/psychopathological traits of patients with TTC.MethodsA survey of three groups was conducted: I) Female post-recovery TTC patients admitted between October 1st 2009 and December 10th 2014, II) Age, gender and geographically matched ST-elevation myocardial infarction (STEMI) patients, and III) Age, gender and geographically matched individuals from the background population. The following questionnaires were used in the survey: the WHO-5 Well-Being Index, Eysenck’s Neuroticism Scale, the Major Depression Inventory, and the anxiety subscale of Symptoms Checklist (SCL-90).ResultsIn total, 173 of 230 invitees (75 %) participated in the study. In comparison to the background controls, TTC patients reported significantly less well-being, more neuroticism, more depression, and more anxiety. The levels of well-being, depression and neuroticism were comparable between TTC and STEMI patients, but the level of anxiety was higher in the TTC patients. There was a negative correlation between the time since TTC admission and the total scores on the psychopathology rating scales.ConclusionsPatients with TTC reported significantly higher anxiety levels compared to both STEMI patients and background controls. However, unlike the STEMI patients, the TTC patients appeared to improve psychologically during the post-recovery phase. This may be a consolation for TTC patients in acute psychological distress.

【 授权许可】

CC BY   
© The Author(s). 2016