In-vivo high resolution imaging of optic nerve head drusen using spectral-domain Optical Coherence Tomography

BMC Medical Imaging

Research Article

Vikram S Brar¹  Ravi K Murthy¹  Sandeep Grover¹  Kakarla V Chalam¹  Laura Storm¹ 

[1] Department of Ophthalmology, College of Medicine, University of Florida, Jacksonville, Florida, USA;

关键词: Retinal Nerve Fibre Layer;    Optic Nerve Head;    Fundus Autofluorescence;    Humphrey Visual Field;    Ancillary Investigation;   

DOI  :  10.1186/1471-2342-10-11

 received in 2010-01-08, accepted in 2010-06-07,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundOptic nerve head drusen (ONHD) are white calcareous deposits, seen either superficially on the optic nerve head or buried within it. Diagnosis of ONHD is made by one or more ways: clinical exam, autofluorescence, ultrasound of the optic nerve, CT scan and/or visual field examination. The present study describes features of ONHD based on another diagnostic modality, the spectral-domain OCT (Spectralis).MethodsThis is a retrospective case series of 5 patients with bilateral ONHD with a best-corrected visual acuity of 20/20 and no other posterior segment pathology. All the patients underwent fundus photography, fundus autofluorescence, B-scan ultrasonography, Spectralis OCT and Humphrey 30-2 threshold visual fields.ResultsAll 5 patients had surface ONHD which were autofluorescent and echodense on B-scan ultrasonography. Spectralis OCT findings in the corresponding areas include 'scattered spots with high reflectivity' casting a shadow underneath. The reflectivity can be distinctly differentiated from the blood vessels on the optic nerve. Two patients had an arcuate scotoma on the Humphrey visual fields. No correlation was found between the changes on Spectralis OCT with that of visual field.ConclusionsSpectralis OCT is another useful ancillary investigation in the diagnosis of ONHD and we describe the features in the present study.

【 授权许可】

Unknown   
© Murthy et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.