Comparison of characteristics of culture-negative pyogenic spondylitis and tuberculous spondylitis: a retrospective study

BMC Infectious Diseases

Research Article

Myoung-don Oh¹  Pyoeng Gyun Choe¹  Eun Jung Kim¹  Wan Beom Park¹  Nam Joong Kim¹  Ji Hwan Bang¹  Sang Won Park¹  Kyoung-Ho Song²  Hong-Bin Kim²  Eu Suk Kim²  Chung-Jong Kim³ 

[1] Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak-ro Jongno-gu, 110-744, Seoul, Republic of Korea;Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak-ro Jongno-gu, 110-744, Seoul, Republic of Korea;Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea;Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak-ro Jongno-gu, 110-744, Seoul, Republic of Korea;Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea;Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea;

关键词: Spondylitis;    Discitis;    Epidural abscess;    Mycobacterium tuberculosis;    Spinal tuberculosis;   

DOI  :  10.1186/s12879-016-1897-0

 received in 2016-02-04, accepted in 2016-10-05,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundDifferences between the characteristics of culture positive pyogenic spondylitis (CPPS) and tuberculous spondylitis (TS) are well known. However, differences between the characteristics of culture negative pyogenic spondylitis (CNPS) and TS have not been reported; these would be more helpful in clinical practice especially when initial microbiologic examination of blood and/or biopsy tissue did not reveal the causative bacteria in patients with infectious spondylitis.MethodsWe performed a retrospective review of the medical records of patients with CNPS and TS. We compared the characteristics of 71 patients with CNPS with those of 94 patients with TS.ResultsPatients with TS had more previous histories of tuberculosis (9.9 vs 22.3 %, p = 0.034), simultaneous tuberculosis other than of the spine (0 vs 47.9 %, p < 0.001), and positive results in the interferon-gamma release assay (27.6 vs 79.2 %, p < 0.001). Fever (15.5 vs. 31.8 %, p = 0.018), psoas abscesses (15.5 vs 33.0 %, p = 0.011), and paravertebral abscesses (49.3 vs. 74.5 %, p = 0.011) were also more prevalent in TS than CNPS.ConclusionsDifferent from or contrary to the previous comparisons between CPPS and TS, fever, psoas abscesses, and paravertebral abscesses are more common in patients with TS than in those with CNPS.

【 授权许可】

CC BY   
© The Author(s). 2016