Initial clinical experience with a novel vertebral augmentation system for treatment of symptomatic vertebral compression fractures: A case series of 26 consecutive patients

BMC Musculoskeletal Disorders

Research Article

Jon E Block¹  Larry E Miller²  Panagiotis Korovessis³  Thomas Repantis³ 

[1] Jon E. Block, PhD, Inc, 2210 Jackson Street, Suite 401, CA 94115, San Francisco, USA;Miller Scientific Consulting, Inc., 422 Mountain Wasp Drive, NC 28715, Biltmore Lake, USA;Jon E. Block, PhD, Inc, 2210 Jackson Street, Suite 401, CA 94115, San Francisco, USA;Orthopaedic Department, General Hospital "Agios Andreas", 1 Tsertidou str, 26224, Patras, Greece;

关键词: Fracture;    Minimally invasive;    Osteoporosis;    Vertebral augmentation;   

DOI  :  10.1186/1471-2474-12-206

 received in 2011-02-11, accepted in 2011-09-22,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundMinimally invasive vertebral augmentation procedures are widely used to treat vertebral compression fractures although procedural polymethylmethacrylate cement leakage remains common. We report herein our initial experience with a novel vertebral augmentation technique designed to treat symptomatic vertebral osteoporotic fractures and osteolytic metastases with minimal cement extravasation.MethodsForty-two vertebral fractures were identified in 26 consecutive patients (mean age 74 ± 9 years). All patients were treated with a novel percutaneous vertebral augmentation device (Kiva® VCF Treatment System, Benvenue Medical, Santa Clara, CA, USA). Indications for surgery included recent (≤ 3 months) symptomatic osteoporotic vertebral fracture (n = 34) and pathologic vertebral fractures (e.g. metabolic bone disease, myeloma, metastasis) (n = 8) located between T10 and S1. Patient outcomes were evaluated pre-treatment and at 2- and 6-month follow-up visits. Postoperative cement extravasation was assessed with computed tomography. Patient-reported back pain was quantified using an 11-point numeric scale. Back-specific functional disability was self-reported with the Oswestry Disability Index on a 0 to 100% scale.ResultsNo cases of intraoperative hypotension, respiratory disturbance, neurological deterioration, infection, or death were observed. There were 2 (4.8%) levels where anterior cement leakage was visible radiographically in patients with osteolyses. No intracanal leakage was observed. Back pain scores improved 71% (p < 0.001) from pre-treatment to the 6-month follow-up. Back function improved 56% from baseline to 6 months (p < 0.001).ConclusionsThe initial clinical experience with the Kiva® System demonstrated significant improvements in back pain and function with minimal and clinically insignificant procedural cement leakage.

【 授权许可】

Unknown   
© Korovessis et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.