An overview of osteoporosis and frailty in the elderly

BMC Musculoskeletal Disorders

Review

Lehana Thabane¹  Mitchell A. H. Levine²  Guowei Li²  George Ioannidis³  Alexandra Papaioannou³  Jonathan D. Adachi⁴ 

[1] Department of Clinical Epidemiology & Biostatistics, McMaster University, 1280 Main Street West, L8S 4L8, Hamilton, ON, Canada;St. Joseph’s Healthcare Hamilton, McMaster University, 25 Charlton Avenue East, L8N 1Y2, Hamilton, ON, Canada;Department of Clinical Epidemiology & Biostatistics, McMaster University, 1280 Main Street West, L8S 4L8, Hamilton, ON, Canada;St. Joseph’s Healthcare Hamilton, McMaster University, 25 Charlton Avenue East, L8N 1Y2, Hamilton, ON, Canada;Programs for Assessment of Technology in Health, Centre for Evaluation of Medicines, L8N 1Y3, Hamilton, ON, Canada;Department of Medicine, McMaster University, 1280 Main Street West, L8S 4L8, Hamilton, ON, Canada;St. Joseph’s Healthcare Hamilton, McMaster University, 25 Charlton Avenue East, L8N 1Y2, Hamilton, ON, Canada;Department of Medicine, McMaster University, 1280 Main Street West, L8S 4L8, Hamilton, ON, Canada;St. Joseph’s Healthcare Hamilton, McMaster University, 25 Charlton Avenue East, L8N 1Y2, Hamilton, ON, Canada;

关键词: Osteoporosis;    Osteoporotic fractures;    Frailty;    Geriatrics;    Ageing;   

DOI  :  10.1186/s12891-017-1403-x

 received in 2016-09-15, accepted in 2017-01-14,  发布年份 2017

来源: Springer

【 摘 要 】

Osteoporosis and osteoporotic fractures remain significant public health challenges worldwide. Recently the concept of frailty in relation to osteoporosis in the elderly has been increasingly accepted, with emerging studies measuring frailty as a predictor of osteoporotic fractures. In this overview, we reviewed the relationship between frailty and osteoporosis, described the approaches to measuring the grades of frailty, and presented current studies and future research directions investigating osteoporosis and frailty in the elderly. It is concluded that measuring the grades of frailty in the elderly could assist in the assessment, management and decision-making for osteoporosis and osteoporotic fractures at a clinical research level and at a health care policy level.

【 授权许可】

CC BY   
© The Author(s). 2017