期刊论文详细信息
The Journal of Headache and Pain
Nonspecific periaqueductal gray lesions on T2WI in episodic migraine
Research Article
Xiaoyan Chen1  Shengyuan Yu1  Shuangfeng Liu2  Lin Ma2  Mengqi Liu2  Zhiye Chen3 
[1] Department of Neurology, Chinese PLA General Hospital, 28 Fuxing Road, 100853, Beijing, China;Department of Radiology, Chinese PLA General Hospital, 28 Fuxing Road, 100853, Beijing, China;Department of Radiology, Chinese PLA General Hospital, 28 Fuxing Road, 100853, Beijing, China;Department of Neurology, Chinese PLA General Hospital, 28 Fuxing Road, 100853, Beijing, China;
关键词: Episodic migraine;    Periaqueductal gray;    Hyperintensity lesions;    Magnetic resonance imaging;   
DOI  :  10.1186/s10194-016-0695-9
 received in 2016-10-05, accepted in 2016-10-20,  发布年份 2016
来源: Springer
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【 摘 要 】

BackgroundThe specific periaqueductal gray (PAG) lesions with migraine-like headache were easily identified on conventional MR images in clinical practice, and the aim of this study is to investigate the nonspecific periaqueductal gray (PAG) lesions in episodic migraine (EM) patients based on T2 weighted imaging (T2WI).MethodsT2WI images were obtained from 18 EM patients and 18 normal controls (NC) on 3.0 T MR system. The images were observed by two experienced radiologists, and the lesions were identified on T2WI by consensus by 2 experienced neuroradiologists blinded to the patient identity. Chi-Square test was performed for the significance test.ResultsRing-like hyperintensity lesions (HILs) around the PAG region were observed in 14 EM patients and in 5 NCs on T2WI. Four EM patients and 13 NCs were normal in PAG region. The significance was revealed by Chi-Square test (P = 0.003).ConclusionHIL of PAG may be the direct evidence of the EM genesis, and the further structural and functional study should be performed to elucidate the neuromechanism of migraine pathogenesis.

【 授权许可】

CC BY   
© The Author(s). 2016

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