The omics in migraine

The Journal of Headache and Pain

Review Article

Elisa Bellei¹  Luigi Alberto Pini²  Giovanna Gentile³  Francesco Marsibilio⁴  Paolo Martelletti⁵  Luana Lionetto⁶  Donata Sabato⁶  Matilde Capi⁶  Maurizio Simmaco⁷ 

[1] Department of Diagnostic Medicine, Clinic and Public Health, University of Modena and Reggio Emilia, Modena, Italy;Inter-Department Headache and Drug Abuse Centre, University of Modena and Reggio Emilia, Modena, Italy;NESMOS Department, Sapienza University of Rome, Rome, Italy;Regional Referral Headache Centre, Sant’Andrea Hospital, Rome, Italy;Regional Referral Headache Centre, Sant’Andrea Hospital, Rome, Italy;Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy;Sant’Andrea Hospital, Advanced Molecular Diagnostics Unit, Via di Grottarossa 1035 – 1039, 00189, Rome, Italy;Sant’Andrea Hospital, Advanced Molecular Diagnostics Unit, Via di Grottarossa 1035 – 1039, 00189, Rome, Italy;NESMOS Department, Sapienza University of Rome, Rome, Italy;

关键词: Genomics;    Proteomics;    Metabolomics;    Migraine;   

DOI  :  10.1186/1129-2377-14-55

 received in 2013-06-06, accepted in 2013-06-22,  发布年份 2013

来源: Springer

【 摘 要 】

The term omics consist of three main areas of molecular biology, such as genomics, proteomics and metabolomics. The omics synergism recognise migraine as an ideal study model, due to its multifactorial nature. In this review, the plainly research data featuring in this complex network are reported and analyzed, as single or multiple factor in pathophysiology of migraine. The future of migraine biomolecular research shall be focused on networking among these different and hierarchical disciplines. We have to look for its Ariadne’s tread, in order to see the whole painting of migraine molecular biology.

【 授权许可】

CC BY   
© Lionetto et al.; licensee Springer. 2013. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.