Excessive daytime sleepiness is associated with an exacerbation of migraine: A population-based study

The Journal of Headache and Pain

Research Article

Chang-Ho Yun¹  Jiyoung Kim²  Soo-Jin Cho³  Won-Joo Kim⁴  Min Kyung Chu⁵  Kwang Ik Yang⁶ 

[1] Clinical Neuroscience Center, Department of Neurology, Seoul National University Bundang Hospital, Seongnam, South Korea;Department of Neurology, Bio Medical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Busan, South Korea;Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, South Korea;Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea;Department of Neurology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, 1 Singil-ro, Yeongdeungpo-gu, 07441, Seoul, South Korea;Sleep Disorders Center, Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan, South Korea;

关键词: Epidemiology;    Excessive daytime sleepiness;    Headache;    Migraine;    Sleep;    Sleepiness;   

DOI  :  10.1186/s10194-016-0655-4

 received in 2016-04-05, accepted in 2016-06-27,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundPrevious studies have shown that migraine and sleep disturbances are closely associated. Excessive daytime sleepiness (EDS) is a common symptom of various types of sleep disturbance. Findings from clinic-based studies suggest that a high percentage of migraineurs experience EDS. However, the prevalence and clinical impact of EDS among migraineurs at the population level have rarely been reported. The objective of this study was to investigate the prevalence and impact of EDS among migraineurs using a population-based sample in Korea.MethodsWe selected a stratified random sample of Koreans aged 19 to 69 years and evaluated them using a semi-structured interview designed to identify EDS, headache type, and the clinical characteristics of migraine. If the score on the Epworth Sleepiness Scale (ESS) was more than or equal to 11, the participant was classified as having EDS.ResultsOf the 2,695 participants that completed the interview, 143 (5.3 %) and 313 (11.6 %) were classified as having migraine and EDS, respectively. The prevalence of EDS was significantly higher in participants with migraine (19.6 %) and non-migraine headache (13.4 %) compared to non-headache controls (9.4 %). Migraineurs with EDS had higher scores on the Visual Analogue Scale (VAS) for headache intensity (6.9 ± 1.8 vs. 6.0 ± 1.9, p = 0.014) and Headache Impact Test-6 (59.8 ± 10.2 vs. 52.5 ± 8.2, p < 0.001) compared to migraineurs without EDS.ConclusionsApproximately 20 % of migraineurs had EDS in this population-based sample. Excessive daytime sleepiness was associated with an exacerbation of some migraine symptoms.

【 授权许可】

CC BY   
© The Author(s). 2016