Association of excessive daytime sleepiness with migraine and headache frequency in the general population

The Journal of Headache and Pain

Research Article

Kari Jorunn Kværner¹  Espen Saxhaug Kristoffersen²  Michael Bjørn Russell³  Håvard Anton Kristiansen³  Knut Stavem⁴ 

[1] Head and Neck Research Group, Research Centre, Akershus University Hospital, Lørenskog, Norway;C3 Centre for Connected Care, Oslo University Hospital, Oslo, Norway;BI Norwegian Business School, Oslo, Norway;Head and Neck Research Group, Research Centre, Akershus University Hospital, Lørenskog, Norway;Department of General Practice, University of Oslo, Oslo, Norway;Head and Neck Research Group, Research Centre, Akershus University Hospital, Lørenskog, Norway;Institute of Clinical Medicine, Campus Akershus University Hospital, University of Oslo, Lørenskog, Norway;Head and Neck Research Group, Research Centre, Akershus University Hospital, Lørenskog, Norway;Institute of Clinical Medicine, Campus Akershus University Hospital, University of Oslo, Lørenskog, Norway;Department of Pulmonary Medicine, Medical Division, Akershus University Hospital, Lørenskog, Norway;Health Services Research Unit, Akershus University Hospital, Lørenskog, Norway;

关键词: Epidemiology;    Excessive daytime sleepiness;    Headache;    Migraine;   

DOI  :  10.1186/s10194-017-0743-0

 received in 2017-02-09, accepted in 2017-03-07,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundSome previous studies have postulated an association between migraine and excessive daytime sleepiness (EDS). This study evaluated the association of EDS with migraine and headache frequency in a general population, after adjusting for potential confounding variables.MethodsThe study was a postal survey of a random age and gender-stratified sample of 40,000 persons aged 20 to 80 years old drawn by the National Population Register in Norway. The questionnaire included questions about migraine, headache, the Epworth sleepiness scale (ESS) and various comorbidities. EDS was defined as ESS > 10. The association of EDS and migraine/headache were analysed by bivariate and multivariable logistic regression analyses.ResultsA total of 21,177 persons responded to the ESS and were included in the analyses. The odds ratio (OR) for EDS was increased for migraineurs (1.42 (95% CI 1.31─1.54), p < 0.001) compared to non-migraineurs; however, this finding was not significant after adjustment for a number of possible confounders. EDS increased with increasing headache frequency, with an OR of 2.74 (95% CI 2.05─3.65), p < 0.001) for those with headache on >179 days per year compared to those without headache in multivariable analysis.ConclusionsIn a general population, the odds for EDS increased significantly with the headache frequency, irrespective of migraine status. EDS was not associated with reported migraine in multivariable analysis.

【 授权许可】

CC BY   
© The Author(s). 2017