Is endoscopic sinus surgery sufficient to modify the evolution of adult AERD? Aspirin desensitization as a maintenance factor: systematic review

Frontiers in Allergy

Allergy

Glenis K. Scadding¹  Eduardo J. Correa²  Diego M. Conti³ 

[1] Department of Allergy & Rhinology, Royal National ENT Hospital, London, United Kingdom;Division of Immunity and Infection, University College, London, United Kingdom;Otolaryngology Department, Hospital Comarcal de la Línea de La Concepción, Cádiz, Spain;The European Forum for Research and Education in Allergy and Airway Diseases Scientific Expert Team Members, Brussels, Belgium;

关键词: AERD;    N-ERD;    ESS;    FESS;    sinus surgery;    ATAD;    aspirin desensitization;    CRSwNP;   

DOI  :  10.3389/falgy.2023.1250178

 received in 2023-06-29, accepted in 2023-08-28,  发布年份 2023

来源: Frontiers

【 摘 要 】

IntroductionAspirin desensitization (AD) and aspirin therapy after desensitization (ATAD) are therapeutic interventions for patients with aspirin-exacerbated respiratory disease (AERD). Our aim is to investigate whether its addition to endoscopic sinus surgery (ESS) improves the overall prognosis of the disease.MethodsA systematic review of the current literature including adult patients with a positive diagnosis of AERD undergoing endoscopic sinus surgery (ESS) in the context or in absence of upper airway comorbidity, prior to AD + ATAD.ConclusionThis review concludes that the surgical approach is beneficial in AERD, but its effects are short—lived. Surgery should be considered initially with subsequent AD + ATAD in AERD patients, due to the sustained improvement achieved compared to those receiving ESS alone.

【 授权许可】

Unknown   
© 2023 Conti, Correa and Scadding.