Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report

Frontiers in Neurology

Neurology

Ying Yuan¹  Ying Tang¹  Ye Deng¹  Wei Zhang¹  Zhigang Li¹  Long Luo¹  Ling Zhu¹  Jun Yin² 

[1] Department of Neurology, Xiangtan Central Hospital, Xiangtan, Hunan, China;Department of Neurology, Xiangya Hospital, Changsha, Hunan, China;

关键词: eperisone hydrochloride;    muscle relaxant;    drug;    tonic;    seizures;    case report;   

DOI  :  10.3389/fneur.2023.1240526

 received in 2023-06-15, accepted in 2023-08-16,  发布年份 2023

来源: Frontiers

【 摘 要 】

Eperisone hydrochloride is a central muscle relaxant used to treat osteoporosis. Seizures are rare side effects of eperisone hydrochloride and have been previously reported in the medical literature in overdose situations but not at regular doses. This case report describes a 42-year-old male painter who developed severe bilateral tonic seizures after the initiation of eperisone hydrochloride at regular doses for low back pain. Symptoms gradually eased in the days following the discontinuation of eperisone hydrochloride and antiepileptic treatment, with no recurrence. This rare adverse drug reaction warrants clinical awareness; however, the mechanisms underlying these adverse reactions remain to be clarified.

【 授权许可】

Unknown   
Copyright © 2023 Luo, Yin, Li, Zhang, Yuan, Tang, Deng and Zhu.