Frontiers in Immunology | |
The mechanisms and factors that induce trained immunity in arthropods and mollusks | |
Immunology | |
Shen Yang1  Xiuli Chen2  Yongzhen Zhao2  Zhongyang Lin3  Zhihong Zheng3  Mingming Zhao3  Defu Yao3  Yueling Zhang3  Jude Juventus Aweya4  | |
[1] College of Ocean Food and Biological Engineering, Fujian Provincial Key Laboratory of Food Microbiology and Enzyme Engineering, Jimei University, Xiamen, Fujian, China;Guangxi Academy of Fishery Sciences, Guangxi Key Laboratory of Aquatic Genetic Breeding and Healthy Aquaculture, Nanning, China;Institute of Marine Sciences and Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, China;Institute of Marine Sciences and Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, China;College of Ocean Food and Biological Engineering, Fujian Provincial Key Laboratory of Food Microbiology and Enzyme Engineering, Jimei University, Xiamen, Fujian, China; | |
关键词: trained immunity; arthropods; mollusks; metabolism; epigenetic modifications; | |
DOI : 10.3389/fimmu.2023.1241934 | |
received in 2023-06-17, accepted in 2023-08-25, 发布年份 2023 | |
来源: Frontiers | |
【 摘 要 】
Besides dividing the organism’s immune system into adaptive and innate immunity, it has long been thought that only adaptive immunity can establish immune memory. However, many studies have shown that innate immunity can also build immunological memory through epigenetic reprogramming and modifications to resist pathogens’ reinfection, known as trained immunity. This paper reviews the role of mitochondrial metabolism and epigenetic modifications and describes the molecular foundation in the trained immunity of arthropods and mollusks. Mitochondrial metabolism and epigenetic modifications complement each other and play a key role in trained immunity.
【 授权许可】
Unknown
Copyright © 2023 Zhao, Lin, Zheng, Yao, Yang, Zhao, Chen, Aweya and Zhang
【 预 览 】
Files | Size | Format | View |
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RO202310125889307ZK.pdf | 1738KB | download |