A cross-sectional study on the association between dietary inflammatory index and hyperuricemia based on NHANES 2005–2018

Frontiers in Nutrition

Nutrition

Feng Li¹  Huanhuan Zhang¹  Ling Zeng¹  Hao Wang¹  Shengmei Qin² 

[1] Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China;West China School of Nursing, Sichuan University, Chengdu, China;Department of Nursing, Stomatological Hospital Southern Medical University, Guangzhou, China;

关键词: dietary inflammatory index;    hyperuricemia;    adults;    the United States;    NHANES;   

DOI  :  10.3389/fnut.2023.1218166

 received in 2023-05-06, accepted in 2023-08-28,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundHyperuricemia is a common condition that can lead to gout and other related diseases. It has been suggested that Inflammatory factors play important role in the development and progression of hyperuricemia. The dietary inflammatory index (DII) enables the assessment of the inflammatory potential of an individual’s diet. This study aimed to investigate the association between DII and hyperuricemia.MethodsThis study was performed based on a cross-sectional dataset from the National Health and Nutrition Examination Survey (NHANES) 2005–2018. Participants aged 18 years and above with dietary intake and serum uric acid level information were included. DII scores were calculated using dietary intake data, based on which participants were categorized into tertiles. Multivariable logistic regression analysis was adopted to investigate the association between DII and hyperuricemia.ResultsAmong a total of 31,781 participants in the analysis, 5,491 had hyperuricemia. After adjusting confounding factors, the odds of hyperuricemia are significantly higher in the second (OR 1.17, 95% CI 1.07–1.29) and third tertiles (OR 1.31, 95% CI 1.19–1.44) relative to the first one.ConclusionThis study suggested that diet with higher inflammatory potential, as measured by DII, is associated with increased hyperuricemia risk. These findings indicated that dietary modification may be a potential approach for hyperuricemia’s prevention and control.

【 授权许可】

Unknown   
Copyright © 2023 Wang, Qin, Li, Zhang and Zeng.