Metabolic syndrome, adiposity, diet, and emotional eating are associated with oxidative stress in adolescents

Frontiers in Nutrition

Nutrition

Juan Miguel Fernández-Alvira¹  Jesús Martínez-Gómez¹  Rodrigo Fernández-Jiménez²  Ramon Estruch³  Ana María Ruiz-León³  Sonia L. Ramírez-Garza⁴  Rosa M. Lamuela-Raventós⁵  Anna Tresserra-Rimbau⁵  Emily P. Laveriano-Santos⁵  Juan J. Moreno⁵  Amaya de Cos-Gandoy⁶  Mercedes de Miguel⁶  Patricia Bodega⁶  Gloria Santos-Beneit⁷ 

[1] Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain;Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain;Hospital Universitario Clínico San Carlos, Madrid, Spain;Centro de Investigación Biomédica En Red en Enfermedades CardioVasculares, Madrid, Spain;Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain;Department of Internal Medicine Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;Department of Nutrition, Food Science and Gastronomy, XIA, School of Pharmacy and Food Sciences, Institute for Nutrition and Food Safety Research, University of Barcelona, Barcelona, Spain;Department of Nutrition, Food Science and Gastronomy, XIA, School of Pharmacy and Food Sciences, Institute for Nutrition and Food Safety Research, University of Barcelona, Barcelona, Spain;Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain;Foundation for Science, Health and Education, Barcelona, Spain;Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain;Foundation for Science, Health and Education, Barcelona, Spain;The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States;

关键词: nutritional status;    nutrition assessment;    fish;    refined cereals;    obesity;    emotion;    anxiety;    depression;   

DOI  :  10.3389/fnut.2023.1216445

 received in 2023-05-03, accepted in 2023-08-15,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundMetabolic syndrome (MS), a condition related to adiposity and oxidative stress, can develop in adolescence, a critical stage in life that impacts health in adulthood. However, there is scarce scientific research about the relationship between lifestyle factors, emotion management, and oxidative stress in this phase of life.AimTo analyze whether nutritional parameters, lifestyle factors, emotion management, and MS in adolescents are associated with oxidative stress measured by the biomarker 8-isoprostane.MethodsA cross-sectional study was carried out in 132 adolescents (48.5% girls, aged 12 ± 0.48 years) and data were collected on nutritional parameters (anthropometric measurements, biochemical analyzes, and blood pressure), lifestyle factors (physical activity, sleep, and diet), and emotion management (self-esteem, emotional eating, and mood). 8-isoprostane was analyzed in spot urine samples. The study population was categorized in three groups (healthy, at-risk, and with MS) using the International Diabetes Federation definition of MS in adolescents. To capture more complex interactions, a multiple linear regression was used to analyze the association between 8-isoprostane and the aforementioned variables.ResultsUrinary 8-isoprostane levels were significantly higher in the MS group compared to the healthy group (1,280 ± 543 pg./mg vs. 950 ± 416 pg./mg respectively). In addition, univariable analysis revealed positive significant associations between 8-isoprostane and body mass index, waist circumference, waist-to-height ratio, body fat percentage, blood lipid profile and glucose, emotional eating, and refined cereal intake. Conversely, a negative significant association was found between 8-isoprostane and sleep duration and fish intake. The multiple linear regression analysis revealed associations between 8-isoprostane and LDL-c (β = 0.173 value of p = 0.049), emotional eating (low β = 0.443, value of p = 0.036; high β = 0.152, value of p = 0.470), refined cereal intake (β =0.191, value of p = 0.024), and fish intake (β = −0.187, value of p = 0.050).ConclusionThe MS group, LDL-c, emotional eating, and high refined cereals and low fish intakes were associated with higher levels of oxidative stress in an adolescent population.

【 授权许可】

Unknown   
Copyright © 2023 Ramírez-Garza, Laveriano-Santos, Moreno, Bodega, de Cos-Gandoy, de Miguel, Santos-Beneit, Fernández-Alvira, Fernández-Jiménez, Martínez-Gómez, Ruiz-León, Estruch, Lamuela-Raventós and Tresserra-Rimbau.