The association between pre-operative malnutrition and post-amputation clinical outcomes: A systematic review

Proceedings of Singapore Healthcare

article

Xiaomei Zheng¹  Mei En Joy Yeo¹  Charles Chin Han Lew¹ 

[1] Department of Dietetics and Nutrition, Ng Teng Fong General Hospital

关键词: Malnutrition;    amputation;    nutritional status;    nutrition assessment;   

DOI  :  10.1177/20101058221094864

学科分类：社会科学、人文和艺术（综合）

来源: Sage Journals

【 摘 要 】

Background: In patients who underwent lower limb amputation (LLA), the prevalence of malnutrition and its associationwith clinical outcomes are unclear.Objectives: This systematic review aims to identify literature and summarise existing information on (1) the prevalence ofmalnutrition in the patients with LLA and (2) the association between pre-operative nutritional status and post-surgery clinicaloutcomes in patients who require amputation.Methods: A search was conducted in four electronic databases (Cochrane Central Register of Controlled Trials (CENTRAL),PubMed, CINAHL and Scopus) to identify eligible studies. The search strategy was based on keywords – amputation,malnutrition and undernutrition. Article were included regardless of the study design; and if they were written in English;included adult patients with lower limb or foot amputation; and performed pre-amputation nutrition assessments.Results: Seven articles met the eligibility criteria. Malnutrition was assessed by biochemistry and/or anthropometry – noneof which are validated nutrition assessment tools. Nevertheless, abnormal biochemistry and/or anthropometry results wereassociated with delayed wound healing, complications and failed amputation compared to normal ranges. The associationbetween abnormal biochemistry and/or anthropometry parameters and mortality was less consistent. Only one study used avalidated nutrition screen tool and found half of the population with LLA were at risk of malnutrition, but no association wasreported.Conclusions: The association between malnutrition and clinical outcomes in patients who underwent LLA remains unclearas all the eligible studies that investigated association used unvalidated nutrition assessment tools. There is an urgent need toaddress this knowledge gap in future research.

【 授权许可】

CC BY|CC BY-NC