Volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study

BMC Oral Health

Research

Sokina Al-Karmati¹  Kiran Acharya²  Mohamed Elhoumed³  Mueataz A. Mahyoub⁴  Essam Ahmed Al-Moraissi⁵  Huanhuan Lv⁶  Sarah Al-Qurmoti⁶  Sisi Bi⁶  Lina Jiao⁶  Jing Zhang⁶  Jinfeng Li⁷  Xiaoru Hou⁸  Haiyan Wu⁹  Xiaoyi Hu⁹  Jing Li^1,10  Zhuo‑Ying Tao^1,11 

[1] College of Dentistry, Ibb University, Ibb, Yemen;Department of Cranio-Maxillofacial Trauma and Plastic Surgery, College of Stomatology, Xi’an Jiaotong University, Xi’an, China;Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Center, 710061, Xi’an, Shaanxi, P.R. China;National Institute of Public Health Research (INRSP), BP. 695, Nouakchott, Mauritania;Department of Internal Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China;Department of Oral and Maxillofacial surgery, Thamar university, Dhamar, Yemen;Key laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, 98West 5th Road, 710004, Xi’an, Shaanxi, China;Department of Cleft Palate-Craniofacial Surgery, College of Stomatology, Xi’an Jiaotong University, 98West 5th Road, 710004, Xi’an, Shaanxi, China;Key laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, 98West 5th Road, 710004, Xi’an, Shaanxi, China;Department of Cleft Palate-Craniofacial Surgery, College of Stomatology, Xi’an Jiaotong University, 98West 5th Road, 710004, Xi’an, Shaanxi, China;Department of Oral and Maxillofacial Surgery, Xi’an Jiaotong University College of Stomatology, 98 West 5th Road, 710004, Xi’an, Shaanxi, China;Key laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, 98West 5th Road, 710004, Xi’an, Shaanxi, China;Department of Cranio-Maxillofacial Trauma and Plastic Surgery, College of Stomatology, Xi’an Jiaotong University, Xi’an, China;Key laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, 98West 5th Road, 710004, Xi’an, Shaanxi, China;Department of Craniofacial Surgery, Xi’an Jiaotong University College of Stomatology, 98 West 5th Road, 710004, Xi’an, Shaanxi, China;Key laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, 98West 5th Road, 710004, Xi’an, Shaanxi, China;Department of Stomatology, Shaanxi Provincial Hospital, 710038, Xi’an, Shaanxi, China;Key laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, 98West 5th Road, 710004, Xi’an, Shaanxi, China;Division of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong. Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong;

关键词: Large jaw cysts;    Ameloblastomas;    Keratocysts;    Enucleation;    Cavity volume residual, Image J;   

DOI  :  10.1186/s12903-023-03307-1

 received in 2023-04-11, accepted in 2023-08-12,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundEnucleation, a surgical procedure, is commonly used to treat large jaw cysts, unicystic ameloblastomas and keratocysts. However, it remains unclear to what extent the jaw bone regenerates after enucleation. We aimed to evaluate the percentage and the survival analysis of jaw bone regeneration, in terms of cavity volume residual (CVR), in patients who underwent enucleation of large jaw cysts, unicystic ameloblastomas and keratocysts.MethodsWe collected data longitudinally from 75 patients who underwent jaw cystic lesions enucleation at the Stomatological Hospital of Xi’an Jiaotong University, between January 2015 and June 2021. All patients had both preoperative and postoperative cone-beam computed tomography (CBCT) imaging data. CBCT images were analyzed using Image J. Changes in the CVR were assessed at various follow-up time points, and the Kaplan-Meier method was utilized to evaluate the CVR over time.ResultsThe patients had a mean age of 31.7 years (range: 5.5–72 years) with 58.66% of them being male. The postoperative CVR was 32.20% at three months, 21.10% at six months, 15.90% at 12 months, and 5.60% at 24 months. The percentage of CVR during follow-up periods for the initial size Quartile (Q)1 (212.54-1569.60 mm3) was substantially lower than those of Q2 and Q3 at and after seven months of follow-up and became statistically significant at the 12-month mark.ConclusionThis study demonstrates that spontaneous bone regeneration can occur after enucleation of large jaw cysts, unicystic ameloblastomas and keratocysts, even without the use of filler materials. The initial size of the lesion had a significant impact on the outcome of cystic lesion enucleation over time. To minimize the risks associated with radiation exposure and expenses, we recommend reducing the frequency of CT imaging follow-ups for patients with small initial cavity sizes (ranging from 212.54 to 1569.60 mm3).

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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