Evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loop

BMC Cardiovascular Disorders

Research

Lijuan Sun¹  Fang Zhang¹  Chengwei Xiao²  Xuebing Zhao² 

[1] Department of Ultrasound, First Hospital of Qinhuangdao, Qinhuangdao, China;Hebei Medical University, Shijiazhuang, China;Department of Ultrasound, First Hospital of Qinhuangdao, Qinhuangdao, China;

关键词: Hypertrophic cardiomyopathy;    Left ventricle;    Pressure-strain loop;    Echocardiography;    Myocardial work;   

DOI  :  10.1186/s12872-023-03519-x

 received in 2023-05-28, accepted in 2023-09-19,  发布年份 2023

来源: Springer

【 摘 要 】

ObjectiveThis study aimed to investigate the value of left ventricular (LV) press-strain loop (PSL) in evaluating global and regional myocardial work (MW) in hypertrophic cardiomyopathy (HCM) patients.MethodsA total of 30 HCM patients with interventricular septum hypertrophy (HCM group) and 35 healthy subjects (control group) were selected from First Hospital of Qinhuangdao. The general clinical data and conventional ultrasound parameters of two groups were acquired. The MW parameters were analyzed using LV PSL. The regional MW parameters in the HCM group were compared between ventricular septum and the free walls of left ventricle.ResultsThe epicardial adipose tissue thickness of the HCM group was significantly greater than that of the control group (P < 0.05). Global work efficiency was significantly reduced, while global wasted work was increased in patients with HCM compared with controls (all P < 0.05). The HCM group was compared in the group, to be specific, in the HCM group, the work index, the work efficiency, and the longitudinal strain on the interventricular septum were lower than those on the free wall (all P < 0.05).ConclusionPSL is more effective than LVEF in assessing left ventricular systolic function in HCM and is able to quantify regional myocardial work in the ventricular septum in HCM patients with preserved LVEF, suggesting a novel idea for clinical diagnosis and assessment.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

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