Patient-reported outcome measures in functional dyspepsia: a systematic review and COSMIN analysis

BMC Gastroenterology

Research

Yan Fei¹  Wenjing Li²  Xinai Wang²  Chenqi Wang²  Yaxuan Wu²  Hao Liu²  Hongling Xiao³ 

[1] Shanghai Tenth People’s Hospital Chongming Branch, Shanghai, China;The School of Graduate, Tianjin University of Traditional Chinese Medicine, Tianjin, China;The School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin, China;

关键词: Functional dyspepsia;    Dyspepsia;    Patient-reported outcome measure;    Measurement properties;   

DOI  :  10.1186/s12876-023-02935-9

 received in 2023-02-20, accepted in 2023-08-26,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundFunctional dyspepsia (FD) as a type of disorders of brain-gut interaction (DBGI), patient self-reporting of its symptoms becomes an important component of clinical outcome assessment. We performed a systematic review using Consensus Based Standards for the Selection of Health Measurement Instruments (COSMIN) guidelines to identify the best available patient-reported outcome measure (PROM) of FD.MethodsThe study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We searched four databases with no date limit, looking for previously confirmed PROMs for evaluating FD symptoms. An overall rating was then assigned based upon COSMIN guidelines, and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was used to assess the level of evidence for psychometric properties of included PROMs.ResultsThirty articles covering outcome indicators of 24 patient reports were included. The Leuven Postprandial Distress Scale (LPDS) showed adequate content validity and moderate quality evidence of adequate internal consistency to generate an A recommendation.ConclusionLPDS is currently the most recommended PROM for patient self-reported FD symptoms. However, it fails to assess two important areas of cross-cultural validity/ measurement invariance and measurement error. Future research can be continuously improved on this basis.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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