Analysis of the association between osteoporosis and muscle strength in Korean adults: a national cross-sectional study

Journal of Health, Population and Nutrition

Research

Ji-Young Choi¹  Young-Mo Yang² 

[1] Department of Food and Nutrition, College of Natural Science and Public Health and Safety, Chosun University, Gwangju, Republic of Korea;Department of Pharmacy, College of Pharmacy, Chosun University, 309 Pilmun-daero, Dong-gu, 61452, Gwangju, Republic of Korea;

关键词: Osteoporosis;    Hand grip strength;    Aging;    Body mass index;    Renal function;    Koreans;    Cross-sectional study;   

DOI  :  10.1186/s41043-023-00443-w

 received in 2022-04-27, accepted in 2023-09-08,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundThis study aimed to examine the associations between osteoporosis and hand grip strength (HGS), a surrogate marker of muscular strength, among Korean adults stratified by body mass index (BMI), age, and renal function.MethodsThis study was conducted using the data obtained from the Korea National Health and Nutrition Examination Survey 2015–2019, a cross-sectional and nationally representative survey performed by the Korea Centers for Diseases Control and Prevention.ResultsOf the 26,855 subjects included in this study, those with low muscle strength (LMS) and normal muscle strength were showed in 4,135 (15.4%) and 22,720 (84.6%) subjects, respectively. The osteoporotic subjects had a higher prevalence rate for LMS than those without osteoporosis after adjusting for age [odds ratio (OR), 1.684; 95% confidence interval (CI), 1.500–1.890). The subjects with osteoporosis and BMI < 18.5 kg/m2 also had a higher prevalence rate for LMS after adjusting for age compared to those with non-osteoporosis and BMI < 18.5 kg/m2 (OR, 1.872; 95% CI, 1.043–3.359). Compared to the non-osteoporotic subjects with estimated glomerular filtration rate (eGFR) ≥ 60 mL/min/1.73 m2, those with osteoporosis and eGFR ≥ 60 mL/min/1.73 m2 had a higher prevalence rate for LMS after controlling for age and sex (OR, 1.630; 95% CI, 1.427–1.862).ConclusionsThe results showed that osteoporosis was likely to contribute to an increased prevalence rate of LMS in terms of HGS. Aging, BMI, and renal function also had significant effects on the association between osteoporosis and LMS. This association is likely to assist in developing better strategies to estimate bone health in clinical or public health practice.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023