Clinical application of endobronchial ultrasonography-guided transbronchial needle aspiration biopsy—a single center, large sample, real-world study

BMC Pulmonary Medicine

Research

Zheng Zhu¹  Chun-li Tang²  Hui-qi Zhou²  Chang-hao Zhong²  Shi-yue Li²  Xiao-bo Chen²  Yu Chen²  Rong-mei Geng²  Zi-qing Zhou² 

[1]Department of Allergy and Clinical Immunology, National Center for Respiratory Medicine, State Key Lab of Respiratory Disease, The first affiliated hospital of Guangzhou Medical University, Guangzhou, China

[2]Department of Respiratory and Critical Care Medicine, National Center for Respiratory Medicine, State Key Lab of Respiratory Disease, The first affiliated hospital of Guangzhou Medical University, 151 Yanjiang Road, 510120, Guangzhou, China

关键词: EBUS-TBNA;    Diagnostic value;    Biopsy;    Lymph node;   

DOI  :  10.1186/s12890-023-02568-4

 received in 2023-04-19, accepted in 2023-07-17,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundEndobronchial ultrasonography-guided transbronchial needle aspiration biopsy (EBUS-TBNA) has been used for more than 10 years in China. Its clinical application and diagnostic value in different diseases with large sample was lack of report.MethodsA retrospective analysis was performed about the application and diagnostic value of EBUS-TBNA in different disease of patients in Respiratory Intervention Center of Guangzhou Institute of Respiratory Health from January 2012 to July 2020.ResultsA total 5758 patients were included with 182 patients excluded for lack of information. Finally, data of 5576 patients (3798 males and 1778 females) were analyzed. For anesthetize, most patients were undergoing general anesthesia of intravenous with spontaneous breathing (69.4%), followed by general anesthesia of intravenous and inhalation with tracheal intubation and mechanical ventilation (17.9%) and conscious sedation and analgesia (12.8%). Lymph nodes were the main sites of biopsy obtained (76.4%). Tumors accounted for the highest proportion of disease (66.4%), followed by infection diseases (9.9%), sarcoidosis (3.9%), lymphoma (1.1%), and others (18.7%). The sensitivity of EBUS-TBNA for diagnosis of tumor was 89.7%, and 40.8% for infection diseases. There were significant differences in the puncture site and proportions of diseases between male and females (both p < 0.05). Higher diagnostic value was found in male patients (p < 0.05).ConclusionEBUS-TBNA has good diagnostic value for different mediastinal and central pulmonary space-occupying lesions diseases, with highest sensitivity for tumors. Higher diagnostic value was found in male patients.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

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