Obesity is associated with quality of sperm parameters in men with infertility: a cross-sectional study

Reproductive Health

Research

Moloud Ghorbani¹  Syavash Babaie²  Mahdieh Hosseinzadeh²  Mina Darand³  Narges Sadeghi⁴  Zahra Salimi⁴ 

[1] Department of Community Nutrition, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran;Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran;Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran;Nutrition and Food Security Research Center and Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran;Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran;

关键词: Obesity;    BMI;    WC;    Sperm parameters;    Male;    Infertility;   

DOI  :  10.1186/s12978-023-01664-2

 received in 2023-04-19, accepted in 2023-08-08,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundPrevious studies examined the effects of obesity on sperm parameters and reported inconsistent results. Thus, the present study aimed to evaluate the association between obesity and the quality of sperm parameters in infertile men.Material and methodsThe present cross-sectional study evaluated 218 infertile men aged 20–50. To this end, the 168-item food frequency questionnaire (FFQ) was utilized to evaluate dietary intake. The anthropometric and biochemical variables were examined using standard methods. Further, the association between obesity and the quality of sperm parameters was evaluated using the controlled linear regression for potential confounders.ResultsThe normal sperm morphology had a significant inverse association with BMI [adjusted β − 0.074, CI (− 0.141 to − 0.008), P = 0.029] and WC [adjusted β − 0.026, CI (− 0.051 to − 0.001), P = 0.038]. Additionally, visceral fat had a marginal inverse association with normal sperm morphology [adjusted β − 0.065, CI (− 0.138 to 0.008), P = 0.079] and non-progressive sperm motility [adjusted β − 0.241, CI (− 0.495 to 0.014), P = 0.063].ConclusionEven though the present results indicated that obesity, abdominal obesity, and visceral fat had inverse associations with normal sperm morphology, more mechanism-based studies should be conducted to confirm these findings.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023