Association between added sugars and kidney stones in U.S. adults: data from National Health and Nutrition Examination Survey 2007–2018

Frontiers in Nutrition

Nutrition

Zhenzhen Yang¹  Tielong Tang²  Pingyu Zhu²  Xiaodong Yu²  Shan Yin²  Zhongbo Du²  Yan Borné³ 

[1] Department of Clinical Laboratory, Nanchong Central Hospital, Nanchong, China;Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China;Nutritional Epidemiology, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden;

关键词: adult;    association;    dietary sugars;    nephrolithiasis;    nutrition surveys;   

DOI  :  10.3389/fnut.2023.1226082

 received in 2023-05-30, accepted in 2023-07-06,  发布年份 2023

来源: Frontiers

【 摘 要 】

PurposeAdded sugar is associated with a variety of adverse health outcomes, but its association with kidney stones is unclear. This study was to determine whether added sugar is associated with kidney stones.Materials and methodsThis nationally representative study used National Health and Nutrition Examination Survey (NHANES) datasets from 2007 to 2018 for analysis. People aged ≥20 years who reported a history of kidney stones and provided dietary recall data on added sugars were included. Weighted proportions, multivariable logistic regression analysis and stratified logistic regression were used to evaluate the associations between added sugars and kidney stones by adjusting potential confounders.ResultsTotally 28,303 adults were included, with weighted mean age [95% confidence interval (CI)] of 48.03 (47.56, 48.51) years, 47.74% (47.09, 48.40%) males and 52.26% (51.60, 52.91%) females. The overall mean (95% CI) energy intake from added sugars was 272.10 (266.59, 277.60) kilocalories. In the fully-adjusted multivariable model, the percentage of energy intake from added sugars was positively correlated with kidney stones. Compared to the first quartile of added sugar energy intake percentage, the population in the fourth quartile had a higher prevalence of kidney stones (OR = 1.39; 95% CI 1.17 to 1.65). Compared with the less than 5% calories from added sugar population, the more than or equal to 25% calories from added sugar had a higher kidney stone prevalence (OR = 1.88; 95% CI 1.52 to 2.32).ConclusionA higher percentage of energy intake from added sugars is significantly associated with a higher prevalence of kidney stones. This study provides cross-sectional evidence for the relationship between added sugars and health outcomes.

【 授权许可】

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Copyright © 2023 Yin, Yang, Zhu, Du, Yu, Tang and Borné.