Light energy transduction in liposome-based artificial cells

Frontiers in Bioengineering and Biotechnology

Bioengineering and Biotechnology

Fabio Mavelli¹  Emiliano Altamura¹  Paola Albanese² 

[1] Department of Chemistry, University of Bari, Bari, Italy;Department of Earth, Environmental and Physical Sciences, University of Siena, Siena, Italy;Department of Biotechnology, Chemistry and Pharmaceutical Sciences, University of Siena, Siena, Italy;

关键词: artificial cell;    multi-compartment system;    membrane proteins;    light transduction;    artificial photosyhthesis;    photosynthetic proteins;    giant vesicle (GV);    liposomes;   

DOI  :  10.3389/fbioe.2023.1161730

 received in 2023-02-08, accepted in 2023-03-14,  发布年份 2023

来源: Frontiers

【 摘 要 】

In this work we review the latest strategies for the bottom-up assembly of energetically autonomous artificial cells capable of transducing light energy into chemical energy and support internalized metabolic pathways. Such entities are built by taking inspiration from the photosynthetic machineries found in nature which are purified and reconstituted directly in the membrane of artificial compartments or encapsulated in form of organelle-like structures. Specifically, we report and discuss recent examples based on liposome-technology and multi-compartment (nested) architectures pointing out the importance of this matter for the artificial cell synthesis research field and some limitations and perspectives of the bottom-up approach.

【 授权许可】

Unknown   
Copyright © 2023 Albanese, Mavelli and Altamura.