Burden of thyroid cancer in North Africa and Middle East 1990–2019

Frontiers in Oncology

Oncology

Seyed Mohammad Tavangar¹  Hamidreza Jamshidi²  Bagher Larijani³  Mohsen Naghavi⁴  Ali H. Mokdad⁴  Sina Azadnajafabad⁵  Sahar Saeedi Moghaddam⁵  Nazila Rezaei⁵  Seyed Aria Nejadghaderi⁵  Farshad Farzadfar⁶  Negar Rezaei⁶ 

[1] Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran;Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran;Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran;Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, United States;Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, United States;Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran;Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran;Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran;

关键词: north africa and middle east;    thyroid cancer;    incidence;    mortality;    disability-adjusted life years;    body mass index;    risk factor;   

DOI  :  10.3389/fonc.2022.955358

 received in 2022-05-28, accepted in 2022-07-22,  发布年份 2022

来源: Frontiers

【 摘 要 】

BackgroundThyroid cancer is the leading cause of mortality and morbidity among cancers of the endocrine system. We aimed to describe the trends of thyroid cancer burden in North Africa and Middle East for 1990–2019.MethodsData on burden of thyroid cancer in North Africa and Middle East from 1990 to 2019 were obtained from the Global Burden of Disease (GBD) Study 2019. Decomposition analysis was used to estimate the effects of population growth, aging, and change in incident numbers on overall change of thyroid cancer incidence. Also, we used the comparative risk assessment framework of GBD to determine the burden of thyroid cancer attributable to a high body mass index (BMI).ResultsIn 2019, the age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) of thyroid cancer were 3.5 (2.9–4) and 0.5 (0.5–0.7) per 100,000, respectively. The highest age-standardized incidence, deaths, and disability-adjusted life year (DALY) rate were in Lebanon, Afghanistan, and United Arab Emirates, respectively. The ASIR of thyroid cancer in region was about 2.5 times higher among women, which had a positive association with increasing age. In 2019, the age-standardized deaths attributable to a high BMI was 16.7% of all deaths due to thyroid cancer. In 1990–2019, the overall change in thyroid cancer incident cases was a 396% increase which was mostly driven by the increase in disease-specific incidence rate (256.8%).ConclusionsWomen, the elderly above about 60 years old, and countries with a higher sociodemographic index showed higher incidence rates of thyroid cancer. Regarding our findings, it is recommended to establish preventive plans by modification in life style like weight reduction programs.

【 授权许可】

Unknown   
Copyright © 2022 Nejadghaderi, Moghaddam, Azadnajafabad, Rezaei, Rezaei, Tavangar, Jamshidi, Mokdad, Naghavi, Farzadfar, Larijani and GBD 2019 NAME Thyroid Cancer Collaborators