Laser-induced forward transfer based laser bioprinting in biomedical applications

Frontiers in Bioengineering and Biotechnology

Bioengineering and Biotechnology

Jinlong Chang¹  Xuming Sun² 

[1] School of Medical Engineering, Xinxiang Medical University, Xinxiang, China;School of Medical Engineering, Xinxiang Medical University, Xinxiang, China;Xinxiang Key Laboratory of Neurobiosensor, Xinxiang Medical University, Xinxiang, China;

关键词: 3D printing;    bioprinting;    laser-induced forward transfer;    tissue engineering;    biomedical applications;   

DOI  :  10.3389/fbioe.2023.1255782

 received in 2023-07-09, accepted in 2023-08-10,  发布年份 2023

来源: Frontiers

【 摘 要 】

Bioprinting is an emerging field that utilizes 3D printing technology to fabricate intricate biological structures, including tissues and organs. Among the various promising bioprinting techniques, laser-induced forward transfer (LIFT) stands out by employing a laser to precisely transfer cells or bioinks onto a substrate, enabling the creation of complex 3D architectures with characteristics of high printing precision, enhanced cell viability, and excellent technical adaptability. This technology has found extensive applications in the production of biomolecular microarrays and biological structures, demonstrating significant potential in tissue engineering. This review briefly introduces the experimental setup, bioink ejection mechanisms, and parameters relevant to LIFT bioprinting. Furthermore, it presents a detailed summary of both conventional and cutting-edge applications of LIFT in fabricating biomolecule microarrays and various tissues, such as skin, blood vessels and bone. Additionally, the review addresses the existing challenges in this field and provides corresponding suggestions. By contributing to the ongoing development of this field, this review aims to inspire further research on the utilization of LIFT-based bioprinting in biomedical applications.

【 授权许可】

Unknown   
Copyright © 2023 Chang and Sun.