Targeting intestinal microecology: potential intervention strategies of traditional Chinese medicine for managing hypertension

Frontiers in Pharmacology

Pharmacology

Yangxi Liu¹  Yingfei Bi¹  Zhao Ge¹  Xianliang Wang¹  Zhiqiang Zhao¹  Shanshan Lin¹  Jingyuan Mao¹  Yujian Fan¹  Zhihua Yang²  Lu Chen³  Zhihui Song³  Yi Wang³ 

[1] First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China;First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China;Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China;Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China;

关键词: intestinal microecology;    traditional Chinese medicine;    hypertension;    gut microbiota;    gut barrier;    short chain fatty acids;   

DOI  :  10.3389/fphar.2023.1171119

 received in 2023-02-21, accepted in 2023-05-15,  发布年份 2023

来源: Frontiers

【 摘 要 】

Hypertension has become one of the major public health problems in the world. At present, the pathogenesis of hypertension has still not been completely elucidated. In recent years, an increasing evidence shows that intestinal microecology is closely related to hypertension, which provides a new thinking for the prevention and treatment of hypertension. Traditional Chinese medicine (TCM) has unique advantages in the treatment of hypertension. Taking intestinal microecology as the target, it is possible to interpreting the scientific connotation of TCM prevention and treatment of hypertension by updating the treatment concept of hypertension, so as to improve the therapeutic effect. In our study, the clinical evidence for TCM treatment of hypertension was systematicly summarized. And the relationship among TCM, intestinal microecology and hypertension was analyzed. In addition, the methods by which TCM regulates intestinal microecology to prevent and treat hypertension were presented, to provide new research ideas for prevention and treatment of hypertension.

【 授权许可】

Unknown   
Copyright © 2023 Yang, Lin, Liu, Song, Ge, Fan, Chen, Bi, Zhao, Wang, Wang and Mao.