Case report: First case of early adenoid cystic carcinoma and squamous cell carcinoma collision cancer treated by endoscopic submucosal dissection

Frontiers in Oncology

Oncology

Yongqiu Wei¹  Qiaozhi Zhou¹  Shutian Zhang¹  Zheng Liang¹  Peng Li¹  Rui Xu² 

[1] Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing, China;Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing, China;

关键词: collision cancer;    early esophageal cancer;    esophageal squamous cell carcinoma;    esophageal adenoid cystic carcinoma;    endoscopic submucosal dissection;   

DOI  :  10.3389/fonc.2023.1072336

 received in 2022-10-17, accepted in 2023-01-23,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundCollision cancer, a rare tumor, rarely occurs in the esophagus. Most reported cases of esophageal collision cancers are advanced cancers that can only be treated with surgery or palliative chemoradiotherapy. Here, we report a rare case of collisional squamous cell carcinoma (SqCC) and adenoid cystic carcinoma (AdCC) that was detected in the early stages by endoscopy.Case summaryA 66-year-old man presented with retrosternal pain after swallowing and underwent endoscopy. Pathological biopsy showed high-grade squamous intraepithelial neoplasia. The lesion was removed by endoscopic submucosal dissection (ESD) after magnification and endoscopic ultrasonography. Postoperative pathology proved that the lesion was collision cancer comprising SqCC and AdCC. After six months of postoperative follow-up, there was no recurrence of esophageal cancer.ConclusionsWe provided a case report related to the diagnosis and treatment of esophageal collision cancer, especially early collision cancer. More research is needed to provide insights into the management of collision cancers.

【 授权许可】

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Copyright © 2023 Liang, Wei, Li, Xu, Zhou and Zhang