Cherenkov Radiation–Based Coincidence Time Resolution Measurements in BGO Scintillators

Frontiers in Physics

Physics

Joshua W. Cates¹  Andrea Gonzalez-Montoro²  Shirin Pourashraf²  Craig S. Levin³ 

[1] Applied Nuclear Physics Program, Lawrence Berkeley National Laboratory, Berkeley, CA, United States;Department of Radiology, Molecular Imaging Program at Stanford University, Stanford, CA, United States;Department of Radiology, Molecular Imaging Program at Stanford University, Stanford, CA, United States;Department of Physics, Stanford University, Stanford, CA, United States;Department of Electrical Engineering, Stanford University, Stanford, CA, United States;Department of Bioengineering, Stanford University, Stanford, CA, United States;

关键词: positron emission tomography;    time of flight;    BGO scintillator;    silicon photomultiplier;    readout electronic;    coincidence time resolution (CTR);    end readout;   

DOI  :  10.3389/fphy.2022.816384

 received in 2021-11-16, accepted in 2022-01-05,  发布年份 2022

来源: Frontiers

【 摘 要 】

Bismuth germanate oxide (BGO) scintillators can be re-introduced in time-of-flight positron emission tomography (TOF-PET) by exploiting the Cherenkov luminescence emitted as a result from 511 keV interactions. Accessing the timing information from the relatively few emitted Cherenkov photons is now possible due to the recent improvements in enhanced near-ultraviolet high-density (NUV-HD) silicon photomultiplier (SiPM) technology, fast and low noise readout electronics, and the development of efficient data post-processing methods. In this work, we aim to develop a scalable detector element able to achieve excellent coincidence time resolution (CTR) required for TOF-PET using BGO scintillator elements of various lengths. The proposed detector element is optically coupled to 3.14 × 3.14 mm2 NUV-sensitive SiPMs mounted on a custom design circuit board. In particular, we have evaluated the CTR performance of BGO crystal elements of dimensions 3 × 3 × 3 mm3, 3 × 3 × 5 mm3, 3 × 3 × 10 mm3, and 3 × 3 × 15 mm3, with chemically etched surfaces and wrapped in Teflon tape. To achieve excellent CTR performance, we apply state-of-the-art post-processing methods during data analysis. Best values of 156 ± 6 ps, 188 ± 5 ps, 228 ± 8 ps, and 297 ± 8 ps CTR FWHM have been achieved for the 3, 5, 10, and 15 mm length BGO crystals, respectively. These values improve to 105 ± 6 ps, 127 ± 8 ps, 133 ± 4 ps, and 189 ± 8 ps CTR FWHM, when only considering the Cherenkov component of the timing signal, which is extracted by considering the events with the fastest rise time (20% of the total data). The accurate classification of the events based on their rise time is possible; thanks to the implementation of a dual threshold approach that sets the lower threshold below one light photon equivalent level and the upper one above the signal amplitude of a single photon avalanche diode (SPAD).

【 授权许可】

Unknown   
Copyright © 2022 Gonzalez-Montoro, Pourashraf, Cates and Levin.