Impact of 1-week preoperative auto-CPAP treatment on postoperative outcomes in patients undergoing heart valve replacement surgery: a prospective randomized controlled trial

Frontiers in Neurology

Neurology

Buqing Ni¹  Shijiang Zhang¹  Wei Lin²  Qi Xu³  Ning Ding⁴  Mei Su⁴  Xilong Zhang⁴ 

[1] Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China;Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China;Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China;Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China;

关键词: obstructive sleep apnea;    continuous positive airway pressure (CPAP);    cardiac valve replacement;    postoperative complication;    hospital stay;   

DOI  :  10.3389/fneur.2023.1152168

 received in 2023-01-27, accepted in 2023-05-16,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundWhether preoperative continuous positive airway pressure (CPAP) treatment improves postoperative outcomes in patients undergoing cardiac valve replacement (CVR) remains unknown.HypothesisThis study was to evaluate the effects of 1-week perioperative auto-continuous positive airway pressure (CPAP) treatment on postoperative heart and pulmonary outcomes in patients with obstructive sleep apnea (OSA) and valvular heart disease.MethodsThirty-two patients with OSA and valvular heart disease were randomly assigned to 1-week CPAP (n = 15) group and non-CPAP treatments (n = 17) group. After the treatment, all patients underwent CVR surgery. The length of ICU and hospital stays, postoperative cardiac and respiratory complications were assessed and compared between the 2 groups.ResultsThe results showed there was no significant difference in the baseline characteristics between the CPAP and non-CPAP treatment groups. The length of postoperative ICU and hospital stays, as well as the duration of mechanical ventilation were significantly reduced in the CPAP treatment group compared to the non-CPAP treatment group; however, there were no significant differences in cardiac complications (postoperative arrhythmias, pacemaker use, first dose of dopamine in the ICU, and first dose of dobutamine in the ICU), and respiratory complications (reintubation and pneumonia).ConclusionWe concluded that in patients underwent CVR, preoperative use of auto-CPAP for OSA significantly decreased the duration of mechanical ventilation, and postoperative stays in the ICU and hospital.Clinical Trial Registration: https://ClinicalTrials.gov, identifier NCT03398733.

【 授权许可】

Unknown   
Copyright © 2023 Su, Lin, Xu, Ni, Zhang, Zhang and Ding.