Cervical HPV infection in Yueyang, China: a cross-sectional study of 125,604 women from 2019 to 2022

Frontiers in Public Health

Public Health

Yu Li¹  Xiaoyun Zhang¹  Chongmei Liu¹  Bochao Xie¹  Min Zeng¹  Jinfeng Hou¹  Yangqing Ge¹  Long Zhu²  Zhihui Zhang³  Manqiu Li⁴  Longyun Wu⁵ 

[1] Department of Gynecology, Yueyang People’s Hospital, Hunan Normal University, Yueyang, China;Department of Pathology, Huarong County People’s Hospital of Hunan Province, Yueyang, China;Department of Pathology, Linxiang People’s Hospital of Hunan Province, Yueyang, China;Department of Pathology, Pingjiang People’s Hospital of Hunan Province, Yueyang, China;Department of Pathology, Yueyang Central Hospital, Yueyang, China;

关键词: human papillomavirus;    genotypes;    prevalence;    epidemiology;    cervical lesions;   

DOI  :  10.3389/fpubh.2023.1210253

 received in 2023-04-22, accepted in 2023-07-24,  发布年份 2023

来源: Frontiers

【 摘 要 】

ObjectiveHuman papillomavirus (HPV) infection is currently the main cause of cervical cancer and precancerous lesions in women. The aim of this study was to investigate the epidemiological characteristics of HPV genotypes among women in Yueyang city and to provide a basis for the prevention and treatment of cervical cancer in this city.MethodsA cross-sectional study was conducted on 125,604 women who had received treatment from eight hospitals in Yueyang city from September 2019 to September 2022. Analysis of the prevalence of HPV in patients.ResultsThe prevalence of HPV was 20.5% (95%CI: 20.2–20.7%), of which the high-risk type (HR-HPV) accounted for 17.5% (95%CI: 17.3–17.7%) and the low-risk type (LR-HPV) accounted for 5.0% (95%CI: 4.9–5.1%). Among the HR-HPV subtypes, the top five in prevalence, from the highest to the lowest, were HPV52 (5.1%), HPV16(2.7%), HPV58 (2.6%), HPV53 (2.4%), and HPV51 (1.7%). The main LR-HPV infection types were HPV81 (2,676 cases, OR = 2.1%; 95%CI, 2.0–2.1%). Among the infected patients, 19,203 cases (OR = 74.3%; 95%CI, 73.8–74.9%) had a single subtype, 4,673 cases (OR = 18.1%; 95%CI, 17.6–18.6%) had two subtypes, and 1957 cases (OR = 7.6%; 95%CI, 7.3–7.9%) had three or more subtypes. HPV prevalence is highest among women <25 years, 55–64 years and ≥ 65 years of age.ConclusionThe prevalence of HPV in women in Yueyang city was 20.5%, with HR-HPV being dominant. As women aged <25 years, 55–64 years, and ≥ 65 years are at a relatively higher risk, more attention should be paid to them for prevention and control of HPV infections.

【 授权许可】

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Copyright © 2023 Hou, Zeng, Liu, Xie, Li, Wu, Zhu, Li, Zhang, Zhang and Ge.