Organ chip research in Europe: players, initiatives, and policies

Frontiers in Bioengineering and Biotechnology

Bioengineering and Biotechnology

Alessandro Blasimme¹  Renan Gonçalves Leonel da Silva² 

[1] Health Ethics and Policy Lab, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland;null;

关键词: organ chip;    tissue chip;    microphysiological systems (MPS);    biomedical engineering;    bioengineering;    knowledge ecosystems;    science policy;    bibliometrics;   

DOI  :  10.3389/fbioe.2023.1237561

 received in 2023-06-09, accepted in 2023-08-17,  发布年份 2023

来源: Frontiers

【 摘 要 】

Background: Organ chips are microfabricated devices containing living engineered organ substructures in a controlled microenvironment. Research on organ chips has increased considerably over the past two decades.Aim: This paper offers an overview of the emerging knowledge ecosystem of organ chip research in Europe. Method: This study is based on queries and analyses undertaken through the bibliometric software Dimensions.ai.Results: Organ chip research has been rapidly growing in Europe in recent years, supported by robust academic science consortia, public-private initiatives, dedicated funding, and science policy instruments. Our data shows that previous investment in basic and fundamental research in centers of excellence in bioengineering science and technology are relevant to future investment in organ chips. Moreover, organ chip research in Europe is characterized by collaborative infrastructures to promote convergence of scientific, technical, and clinical capabilities.Conclusion: According to our study, the knowledge ecosystem of organ chip research in Europe has been growing sustainably. This growth is due to relevant institutional diversity, public-private initiatives, and ongoing research collaborations supported by robust funding schemes.

【 授权许可】

Unknown   
Copyright © 2023 da Silva and Blasimme.