Comparative genomics of food-derived probiotic Lactiplantibacillus plantarum K25 reveals its hidden potential, compactness, and efficiency

Frontiers in Microbiology

Microbiology

Abid Sarwar¹  Yang Zhennai¹  Tariq Aziz²  Muhammad Aqib Shabbir³  Muhammad Naveed³  Ayaz Ali Khan⁴  Abdullah F. Alasmari⁵  Abdulrahman Alsahammari⁵  Metab Alharbi⁵ 

[1] Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center for Food Additives, Beijing Technology and Business University, Beijing, China;Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center for Food Additives, Beijing Technology and Business University, Beijing, China;Laboratory of Animal Health, Food Hygiene, and Quality, Department of Agriculture, University of Ioannina, Arta, Greece;Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan;Department of Biotechnology, University of Malakand, Chakdara, Pakistan;Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;

关键词: L. plantarum;    comparative genomics;    bacteriocin;    nucleotide identity;    genomic potential;   

DOI  :  10.3389/fmicb.2023.1214478

 received in 2023-04-29, accepted in 2023-05-18,  发布年份 2023

来源: Frontiers

【 摘 要 】

This study aimed to investigate the intricate genetic makeup of the Lactiplantibacillus plantarum K25 strain by conducting a comprehensive analysis of comparative genomics. The results of our study demonstrate that the genome exhibits a high-level efficiency and compactness, comprising a total of 3,199 genes that encode proteins and a GC content of 43.38%. The present study elucidates the evolutionary lineage of Lactiplantibacillus plantarum strains through an analysis of the degree of gene order conservation and synteny across a range of strains, thereby underscoring their closely interrelated evolutionary trajectories. The identification of various genetic components in the K25 strain, such as bacteriocin gene clusters and prophage regions, highlights its potential utility in diverse domains, such as biotechnology and medicine. The distinctive genetic elements possess the potential to unveil innovative therapeutic and biotechnological remedies in future. This study provides a comprehensive analysis of the L. plantarum K25 strain, revealing its remarkable genomic potential and presenting novel prospects for utilizing its unique genetic features in diverse scientific fields. The present study contributes to the existing literature on Lactiplantibacillus plantarum and sets the stage for prospective investigations and practical implementations that leverage the exceptional genetic characteristics of this adap organism.

【 授权许可】

Unknown   
Copyright © 2023 Aziz, Naveed, Shabbir, Sarwar, Ali Khan, Zhennai, Alharbi, Alsahammari and Alasmari.