Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study

Frontiers in Nutrition

Nutrition

Wei Liao¹  Chongjian Wang¹  Xiaokang Dong¹  Xiaotian Liu¹  Lei Yin²  Dongwei Liu²  Zhangsuo Liu²  Zhaohui Zheng³ 

[1] Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China;Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China;Department of Rheumatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China;

关键词: beans intake;    chronic kidney disease;    albuminuria;    kidney injury;    rural adults;   

DOI  :  10.3389/fnut.2023.1117517

 received in 2022-12-06, accepted in 2023-03-14,  发布年份 2023

来源: Frontiers

【 摘 要 】

Background and aimsDietary factors play an important role in the development of chronic kidney disease (CKD). However, evidence on the relationship of beans consumption with CKD remains limited and inconclusive, especially in the middle-and low-income populations. The current study aimed to investigate the relationships of beans intake with indicators of kidney injury and CKD prevalence in rural adults.MethodsA total of 20,733 rural adults from the Henan Rural Cohort Study in 2018–2022 were included. The total beans intake was collected using a validated food frequency questionnaire. Indicators of kidney injury and CKD was determined by the estimated glomerular filtration rate and the urinary albumin to creatinine ratio. Generalized linear regression and logistic regression models were applied to estimate the relationship of beans intake with continuous and dichotomized indicators of renal function, respectively.ResultsOf the 20,733 participants, 2,676 (12.91%) subjects were identified as CKD patients. After adjusting for potential confounders, participants in the higher quartiles of beans intake had a lower prevalence of CKD (odds ratio and 95% confidence interval, OR (95%CI); Q2: 0.968(0.866–1.082); Q3: 0.836(0.744–0.939); Q4: 0.854(0.751–0.970)) and albuminuria (Q2: 0.982(0.875–1.102); Q3: 0.846(0.750–0.954); Q4: 0.852 (0.746–0.973)), compared with the Q1. Per 50 g/day increment in beans intake was significantly associated with a 5 and 4% decreased prevalence of albuminuria and CKD, respectively. These inverse relationships were also significant in the subgroups of men, elder, and high-income participants (p < 0.05).ConclusionDietary beans intake was inversely associated with the prevalence of albuminuria and CKD in rural adults, suggesting that promoting soy food intake might help reduce the occurrence of CKD in rural adults.

【 授权许可】

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Copyright © 2023 Yin, Dong, Liao, Liu, Zheng, Liu, Wang and Liu.