The oral manifestations and related mechanisms of COVID-19 caused by SARS-CoV-2 infection

Frontiers in Cellular Neuroscience

Neuroscience

Kin Yip Tam¹  Feng Gao²  Ou Sha²  Xianxiong Chen²  Nianhong Qin³  Xia Wang³  Weiming Lin³  Chengfei Zhang⁴  Mingxia Zhang⁵ 

[1] Faculty of Health Sciences, University of Macau, Macau, Macau SAR, China;School of Dentistry, Shenzhen University Medical School, Shenzhen, China;Shenzhen University Medical School, Shenzhen, China;Shenzhen University Medical School, Shenzhen, China;School of Dentistry, The University of Hong Kong, Hong Kong, Hong Kong SAR, China;The Third People’s Hospital of Shenzhen, Shenzhen, China;

关键词: COVID-19;    SARS-CoV-2;    oral manifestations;    ACE2 receptor;    TMPRSS2;    influential factors;   

DOI  :  10.3389/fncel.2022.1006977

 received in 2022-07-29, accepted in 2022-12-13,  发布年份 2023

来源: Frontiers

【 摘 要 】

Coronavirus disease 2019 (COVID-19) was reported to be associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, and patients present mostly with respiratory symptoms. There have been an increasing number of reports on oral manifestations, and some of these signs are informative in terms of identifying SARS-CoV-2 infection. The goal of present study was to review and synthesize the clinical characteristics and underlying mechanisms of COVID-19 oral manifestations, as well as to evaluate the factors influencing SARS-CoV-2 infectivity, in order to conduct further in-depth investigations and help clinicians diagnose COVID-19 patients exhibiting oral symptoms.

【 授权许可】

Unknown   
Copyright © 2023 Lin, Gao, Wang, Qin, Chen, Tam, Zhang, Zhang and Sha.