Adherence, reliability, and variability of home spirometry telemonitoring in cystic fibrosis

Frontiers in Pediatrics

Pediatrics

Julie Macey¹  Grégory Boucher¹  François Gallode¹  Stéphanie Bui²  Patrick Berger³  Raphaël Enaud³  Fabien Beaufils³  Michael Fayon³ 

[1] CHU Bordeaux, Département de Pédiatrie, CIC-P 1401, Service d’Anatomopathologie, Service d’Exploration Fonctionnelle Respiratoire, Bordeaux, France;CHU Bordeaux, Département de Pédiatrie, CIC-P 1401, Service d’Anatomopathologie, Service d’Exploration Fonctionnelle Respiratoire, Bordeaux, France;INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, Centre d’Investigation Clinique (CIC-P 1401), Bordeaux, France;Univ. Bordeaux, Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, Bordeaux Imaging Center, Bordeaux, France;CHU Bordeaux, Département de Pédiatrie, CIC-P 1401, Service d’Anatomopathologie, Service d’Exploration Fonctionnelle Respiratoire, Bordeaux, France;INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, Centre d’Investigation Clinique (CIC-P 1401), Bordeaux, France;

关键词: cystic fibrosis;    telemonitoring;    spirometry;    reliability;    adherence - compliance - persistance;   

DOI  :  10.3389/fped.2023.1111088

 received in 2022-11-29, accepted in 2023-02-06,  发布年份 2023

来源: Frontiers

【 摘 要 】

IntroductionForced spirometry is the gold standard to assess lung function, but its accessibility may be limited. By contrast, home spirometry telemonitoring allows a multi-weekly lung function follow-up but its real-life adherence, reliability, and variability according to age have been poorly studied in patients with CF (PwCF). We aimed to compare real-life adherence, reliability and variability of home spirometry between children, teenagers and adults with CF.MethodsThis real-life observational study included PwCF followed for six months in whom lung function (i.e, forced expiratory volume maximum in 1 s (FEV1), forced vital capacity (FVC), forced mid-expiratory flow (FEF) and FEV1/FVC ratio) was monitored by both conventional and home spirometry between July 2015 and December 2021. The adherence, reliability and variability of home spirometry was assessed in all PwCF and compared between children (<12years old), teenagers (12–18 years old) and adults.Results174 PwCF were included (74 children, 43 teenagers and 57 adults). Home spirometry was used at least one time per week by 64.1 ± 4.9% PwCF, more frequently in children and teenagers than in adults (79.4 ± 2.9%, 69.2 ± 5.5% and 40.4 ± 11.5% respectively). The reliability to conventional lung function testing was good for all assessed parameters (e.g., FEV1: r = 0.91, p < 0.01) and the variability over the 6 months of observation was low (FEV1 coefficient of variation = 11.5%). For each parameter, reliability was better, and the variability was lower in adults than in teenagers than in childrenConclusionHome spirometry telemonitoring appears to be a reliable tool for multi-weekly lung function follow-up of PwCF.

【 授权许可】

Unknown   
© 2023 Beaufils, Enaud, Gallode, Boucher, Macey, Berger, Fayon and Bui.